간 절제 수술 전후 영양 지표의 변화

Abstract

Purpose : Most of patients with hepatocellular carcinoma (HCC) have underlying liver cirrhosis. Liver cirrhosis is frequently associated with malnutrition. Malnutrition influences the outcomes after liver resection. . The aim of this study is to investigate the change of the various nutritional indices after liver resection. Materials and Methods : We performed a prospective study in 39 patients with HCC and measured the anthropometric indices and biochemical parameters before and 3 months after liver resection. Results : There were 26 male and 13 female. The mean age was 52.9 years old in male, 52.8 years old in female. According to the extent of liver resection, the all biochemical parameters except glucose and fat free mass showed a significant change in minor resection group. All biochemical parameters and anthropometric indices except triceps skinfold thickness showed a significant change in major resection group. The biochemical parameters showed a more significant change than that of anthropometric indices in patients with good residual liver function regardless of the extent of live resection. However, all nutritional assessment indices could not showed a significant change in patients with poor residual liver function. Conclusion : The biochemical parameters are more informative than the anthropometric indices in patients with good residual liver function underwent hepatectomy for nutritional assessments. The further study for correlation improvement of the biochemical parameters and improvement of nutrition status should be needed. The largescale study may be needed to assess the superiority of any nutritional assessment indices in patients with poor residual liver function.