Adult ; Electrocardiography ; Fever/complications* ; Humans ; Long QT Syndrome/diagnosis* ; Long QT Syndrome/etiology* ; Male ; Ventricular Fibrillation/diagnosis* ; Ventricular Fibrillation/etiology*
Keywords
Sudden cardiac death ; long QT syndrome ; fever
Abstract
Long QT syndrome is associated with lethal tachyarrhythmia that can lead to syncope, seizure, and sudden death. Congenital long QT syndrome is a genetic disorder, characterized by delayed cardiac repolarization and prolongation of the QT interval on the electrocardiogram (ECG). Type 2 congenital long QT is linked to mutations in the human ether a go-go-related gene (HERG). There are environmental triggers of adverse cardiac events such as emotional and acoustic stimuli, but fever can also be a potential trigger of life-threatening arrhythmias in long QT syndrome type 2 patients. Herein, we report a healthy young man who experienced fever-induced polymorphic ventricular tachycardia and QT interval prolongation.