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Immunoglobulin G4-related hypertrophic pachymeningitis involving cerebral parenchyma.

Authors
 Eui Hyun Kim  ;  Se Hoon Kim  ;  Jin Mo Cho  ;  Jung Yong Ahn  ;  Jong Hee Chang 
Citation
 Journal of Neurosurgery, Vol.115(6) : 1242-1247, 2011 
Journal Title
 Journal of Neurosurgery 
ISSN
 0022-3085 
Issue Date
2011
Abstract
The authors report a case of IgG4-related hypertrophic pachymeningitis that involved cerebral parenchyma. The mass was removed surgically. Histopathological studies showed diffuse infiltration of lymphoplasmacytic cells without evidence of Langerhans histiocytes or meningothelial cells. Immunoglobulin G4 was strongly positive on immunohistochemical staining. The Gd-enhanced lesion deep inside brain parenchyma was completely resolved after 3 months of oral corticosteroid medication. A nodular type of hypertrophic pachymeningitis that mimics a meningioma is rare. Nevertheless, preoperative presumption is very important, and immunohistochemical studies for IgG4 may be helpful in the differential diagnosis.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94799
DOI
10.3171/2011.7.JNS1166
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실)
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Pathology (병리학교실)
Yonsei Authors
김세훈(Kim, Se Hoon) ; 김의현(Kim, Eui Hyun) ; 안정용(Ahn, Jung Yong) ; 장종희(Chang, Jong Hee)
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Full Text
http://thejns.org/doi/full/10.3171/2011.7.JNS1166
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