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Clinical Outcomes and Risk Factors of Rebleeding Following Endoscopic Therapy for Nonvariceal Upper Gastrointestinal Hemorrhage

Authors
 Ki Tae Suk  ;  Hyun-Soo Kim  ;  Chang Seob Lee  ;  Il Young Lee  ;  Moon Young Kim  ;  Jae Woo Kim  ;  Soon Koo Baik  ;  Sang Ok Kwon  ;  Dong Ki Lee  ;  Young Lim Ham 
Citation
 Korean Journal of Gastrointestinal Endoscopy (대한소화기내시경학회지), Vol.44(2) : 93-100, 2011 
Journal Title
Korean Journal of Gastrointestinal Endoscopy(대한소화기내시경학회지)
ISSN
 1225-7001 
Issue Date
2011
Keywords
Endoscopy ; Gastrointestinal hemorrhage ; Risk factors ; Therapy
Abstract
Background/Aims: Rebleeding after endoscopic therapy for non-variceal upper gastrointestinal hemorrhage (NGIH) is the most important predictive factor of mortality. We evaluated the risk factors of rebleeding in patients undergoing endoscopic therapy for the NGIH. Methods: Between January 2003 and January 2007, 554 bleeding events in 487 patients who underwent endoscopic therapy for NGIH were retrospectively enrolled. We reviewed the clinicoendoscopical characteristics of patients with rebleeding and compared them with those of patients without rebleeding. Results: The incidence of rebleeding was 21.7% (n=120). In the multivariate analysis, initial hemoglobin level ≤9 g/dL (p=0.002; odds ratio [OR], 2.433), inexperienced endoscopist with less than 2 years of experience in therapeutic endoscopy (p=0.001; OR, 2.418), the need for more 15 cc of epinephrine (p=0.001; OR, 2.570), injection therapy compared to thermal and injection therapy (p=0.001; OR, 2.840), and comorbidity with chronic renal disease (p=0.004; OR, 2.908) or liver cirrhosis (p=0.010; OR, 2.870) were risk factors for rebleeding following endoscopic therapy. Conclusions: Together with patients with low hemoglobin level at presentation, chronic renal disease, liver cirrhosis, the need for more 15 cc of epinephrine, or therapy done by inexperienced endoscopist were risk factors for the development of rebleeding
Files in This Item:
T201104643.pdf Download
DOI
10.5946/ce.2011.44.2.93
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Lee, Dong Ki(이동기) ORCID logo https://orcid.org/0000-0002-0048-9112
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94765
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