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Primary intestinal lymphangiectasia diagnosed by capsule endoscopy and double balloon enteroscopu

Authors
 Tak Geun Oh  ;  Joo Won Chung  ;  Hee Man Kim  ;  Seok-Joo Han  ;  Jin Sung Lee  ;  Jung Yeob Park  ;  Si Young Song 
Citation
 WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY, Vol.3(11) : 235-240, 2011 
Journal Title
WORLD JOURNAL OF GASTROINTESTINAL ENDOSCOPY
Issue Date
2011
Keywords
Capsule endoscopy ; Chromosome 4q25 ; Chromosome deletion ; Double balloon enteroscopy ; Primary intestinal lymphangiectasia
Abstract
Primary intestinal lymphangiectasia (PIL) is a rare disorder characterized by dilated intestinal lymphatics and the development of protein-losing enteropathy. Patients with PIL develop hypoalbuminemia, hypocalcemia, lymphopenia and hypogammaglobulinemia, and present with bilateral lower limb edema, fatigue, abdominal pain and diarrhea. Endoscopy reveals diffusely elongated, circumferential and polypoid mucosae covered with whitish enlarged villi, all of which indicate intestinal lymphangiectasia. Diagnosis is confirmed by characteristic tissue pathology, which includes dilated intestinal lymphatics with diffusely swollen mucosa and enlarged villi. The prevalence of PIL has increased since the introduction of capsule endoscopy. The etiology and prevalence of PIL remain unknown. Some studies have reported that several genes and regulatory molecules for lymphangiogenesis are related to PIL. We report the case of a patient with PIL involving the entire small bowel that was confirmed by capsule endoscopy and double-balloon enteroscopy-guided tissue pathology who carried a deletion on chromosome 4q25. The relationship between this deletion on chromosome 4 and PIL remains to be investigated.
Files in This Item:
T201104299.pdf Download
DOI
10.4253/wjge.v3.i11.235
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hee Man(김희만) ORCID logo https://orcid.org/0000-0002-7983-1928
Park, Jeong Youp(박정엽) ORCID logo https://orcid.org/0000-0003-0110-8606
Song, Si Young(송시영) ORCID logo https://orcid.org/0000-0002-1417-4314
Oh, Tak Geun(오탁근)
Chung, Joo Won(정주원)
Han, Seok Joo(한석주) ORCID logo https://orcid.org/0000-0001-5224-1437
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94683
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