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Discovery of artemisinin-glycolipid hybrids as anti-oral cancer agents

DC Field Value Language
dc.contributor.author박광균-
dc.contributor.author정원윤-
dc.date.accessioned2014-12-20T17:27:59Z-
dc.date.available2014-12-20T17:27:59Z-
dc.date.issued2011-
dc.identifier.issn0009-2363-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/94655-
dc.description.abstractNovel artemisinin-glycolipid hybrids were directly synthesized from 12β (C-C)-type deoxoartemisinin and glycolipid and exhibited exceptional in vitro anticancer activity, particularly against the oral carcinoma cancer cell lines, respectively. The artemisinin-glycolipid hybrids, with effective concentrations under 20 µM, demonstrated better anticancer activity than either artemisinin or glycolipid alone and showed five times more anti-oral cancer activity than either cisplatin or paclitaxel-
dc.description.statementOfResponsibilityopen-
dc.format.extent1471~1475-
dc.relation.isPartOfCHEMICAL & PHARMACEUTICAL BULLETIN-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAntineoplastic Agents/chemical synthesis-
dc.subject.MESHAntineoplastic Agents/chemistry*-
dc.subject.MESHAntineoplastic Agents/pharmacology*-
dc.subject.MESHArtemisia/chemistry-
dc.subject.MESHArtemisinins/chemical synthesis-
dc.subject.MESHArtemisinins/chemistry*-
dc.subject.MESHArtemisinins/pharmacology*-
dc.subject.MESHCarcinoma/drug therapy-
dc.subject.MESHCell Line, Tumor-
dc.subject.MESHDrug Screening Assays, Antitumor-
dc.subject.MESHGlycolipids/chemical synthesis-
dc.subject.MESHGlycolipids/chemistry*-
dc.subject.MESHGlycolipids/pharmacology*-
dc.subject.MESHHumans-
dc.subject.MESHMouth Neoplasms/drug therapy-
dc.subject.MESHNeoplasms/drug therapy-
dc.titleDiscovery of artemisinin-glycolipid hybrids as anti-oral cancer agents-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Oral Biology (구강생물학)-
dc.contributor.googleauthorJérémy RICCI-
dc.contributor.googleauthorMinkyu KIM-
dc.contributor.googleauthorWon-Yoon CHUNG-
dc.contributor.googleauthorKwang-Kyun PARK-
dc.contributor.googleauthorMankil JUNG-
dc.identifier.doi10.1248/cpb.59.1471-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01429-
dc.contributor.localIdA03676-
dc.relation.journalcodeJ00509-
dc.identifier.eissn1347-5223-
dc.identifier.pmid22130368-
dc.subject.keywordartemisinin-
dc.subject.keywordglycolipid-
dc.subject.keywordhybrid-
dc.subject.keywordanti-oral cancer activity-
dc.contributor.alternativeNamePark, Kwang Kyun-
dc.contributor.alternativeNameChung, Won Yoon-
dc.contributor.affiliatedAuthorPark, Kwang Kyun-
dc.contributor.affiliatedAuthorChung, Won Yoon-
dc.rights.accessRightsfree-
dc.citation.volume59-
dc.citation.number12-
dc.citation.startPage1471-
dc.citation.endPage1475-
dc.identifier.bibliographicCitationCHEMICAL & PHARMACEUTICAL BULLETIN, Vol.59(12) : 1471-1475, 2011-
dc.identifier.rimsid27659-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Biology (구강생물학교실) > 1. Journal Papers
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