Cited 62 times in
The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김영대 | - |
dc.contributor.author | 김진권 | - |
dc.contributor.author | 남정모 | - |
dc.contributor.author | 남효석 | - |
dc.contributor.author | 이혜선 | - |
dc.contributor.author | 차명진 | - |
dc.contributor.author | 허지회 | - |
dc.date.accessioned | 2014-12-20T17:25:26Z | - |
dc.date.available | 2014-12-20T17:25:26Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0021-9150 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/94575 | - |
dc.description.abstract | OBJECTIVE: Arterial stiffness is associated with cardiovascular risk factors and atherosclerosis. Measurement of pulse wave velocity (PWV) is one of the most representative and noninvasive techniques for assessing arterial stiffness. We investigated the association of cerebral atherosclerosis with brachial-ankle PWV (baPWV) in acute ischemic stroke patients. If present, we sought to determine whether the relationship differed between atherosclerosis in the intracranial artery and atherosclerosis in the extracranial artery. METHODS: We included 801 patients with acute ischemic stroke who had undergone angiographic study and baPWV measurement between January 2007 and May 2010. Patients with cerebral artery atherosclerosis were categorized into those with intracranial atherosclerosis, those with extracranial atherosclerosis and those with both intracranial and extracranial atherosclerosis. We determined factors that were associated with baPWV. RESULTS: Univariate and multivariate analyses showed that high baPWV was significantly associated with older age, lower body mass index, higher brachial systolic pressure, and diabetes mellitus. Increased baPWV was associated with the presence of atherosclerosis (≥ 50% stenosis) in the intracranial cerebral artery as well as in both the intracranial and extracranial arteries, but not with atherosclerosis in the extracranial cerebral artery. The burden of intracranial cerebral atherosclerosis, which was assessed based on the number of arteries with atherosclerosis, was also closely associated with baPWV. CONCLUSION: Arterial stiffness was associated with the presence and burden of intracranial cerebral atherosclerosis in stroke patients, but was not associated with the extracranial cerebral atherosclerosis. These findings suggest a potential pathophysiological association between increased arterial stiffness and intracranial cerebral atherosclerosis. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 887~891 | - |
dc.relation.isPartOf | ATHEROSCLEROSIS | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angiography, Digital Subtraction | - |
dc.subject.MESH | Ankle Brachial Index | - |
dc.subject.MESH | Brain Ischemia/diagnosis | - |
dc.subject.MESH | Brain Ischemia/epidemiology | - |
dc.subject.MESH | Brain Ischemia/physiopathology* | - |
dc.subject.MESH | Cerebral Angiography/methods | - |
dc.subject.MESH | Cerebral Arteries/diagnostic imaging | - |
dc.subject.MESH | Cerebral Arteries/physiopathology* | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Elasticity | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Intracranial Arteriosclerosis/diagnosis | - |
dc.subject.MESH | Intracranial Arteriosclerosis/epidemiology | - |
dc.subject.MESH | Intracranial Arteriosclerosis/physiopathology* | - |
dc.subject.MESH | Linear Models | - |
dc.subject.MESH | Magnetic Resonance Angiography | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Multivariate Analysis | - |
dc.subject.MESH | Peripheral Arterial Disease/diagnosis | - |
dc.subject.MESH | Peripheral Arterial Disease/epidemiology | - |
dc.subject.MESH | Peripheral Arterial Disease/physiopathology* | - |
dc.subject.MESH | Pulsatile Flow* | - |
dc.subject.MESH | Registries | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Assessment | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Stroke/diagnosis | - |
dc.subject.MESH | Stroke/epidemiology | - |
dc.subject.MESH | Stroke/physiopathology* | - |
dc.subject.MESH | Tomography, X-Ray Computed | - |
dc.title | The association between cerebral atherosclerosis and arterial stiffness in acute ischemic stroke | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Preventive Medicine (예방의학) | - |
dc.contributor.googleauthor | Jinkwon Kim | - |
dc.contributor.googleauthor | Myoung-Jin Cha | - |
dc.contributor.googleauthor | Dong Hyun Lee | - |
dc.contributor.googleauthor | Hye Sun Lee | - |
dc.contributor.googleauthor | Chung Mo Nam | - |
dc.contributor.googleauthor | Hyo Suk Nam | - |
dc.contributor.googleauthor | Young Dae Kim | - |
dc.contributor.googleauthor | Ji Hoe Heo | - |
dc.identifier.doi | 10.1016/j.atherosclerosis.2011.09.013 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00702 | - |
dc.contributor.localId | A01012 | - |
dc.contributor.localId | A01264 | - |
dc.contributor.localId | A01273 | - |
dc.contributor.localId | A03993 | - |
dc.contributor.localId | A04369 | - |
dc.contributor.localId | A03312 | - |
dc.relation.journalcode | J00260 | - |
dc.identifier.eissn | 1879-1484 | - |
dc.identifier.pmid | 21974846 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0021915011009178 | - |
dc.subject.keyword | Arterial stiffness | - |
dc.subject.keyword | Atherosclerosis | - |
dc.subject.keyword | Pulse wave velocity | - |
dc.subject.keyword | Ischemic stroke | - |
dc.contributor.alternativeName | Kim, Young Dae | - |
dc.contributor.alternativeName | Kim, Jin Kwon | - |
dc.contributor.alternativeName | Nam, Jung Mo | - |
dc.contributor.alternativeName | Nam, Hyo Suk | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Cha, Myoung Jin | - |
dc.contributor.alternativeName | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Kim, Young Dae | - |
dc.contributor.affiliatedAuthor | Kim, Jin Kwon | - |
dc.contributor.affiliatedAuthor | Nam, Jung Mo | - |
dc.contributor.affiliatedAuthor | Nam, Hyo Suk | - |
dc.contributor.affiliatedAuthor | Cha, Myoung Jin | - |
dc.contributor.affiliatedAuthor | Heo, Ji Hoe | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 219 | - |
dc.citation.number | 2 | - |
dc.citation.startPage | 887 | - |
dc.citation.endPage | 891 | - |
dc.identifier.bibliographicCitation | ATHEROSCLEROSIS, Vol.219(2) : 887-891, 2011 | - |
dc.identifier.rimsid | 27428 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.