Head and neck neoplasms ; Radiotherapy ; Tooth extraction ; Wound healing
Abstract
Background: Teeth requiring extraction before radiotherapy in head & neck cancer patients should be removed as long as possible before the initiation
of radiation therapy. Conventionally, a minimum 2-week waiting primary healing period is recommended. Although the above 2-week period is
ideal, it was not uncommon for the radiotherapist and cancer patient to feel an urgent need to process with radiotherapy despite the need for dental
care. Therefore, alternative approaches for early radiotherapy, including conservative endodontic treatment and a 1-week waiting primary healing
period after dental extraction at the time of radiotherapy, were considered and applied based on the experimental study
Materials and Methods: Eighteen dogs were processed for histopathologic wound healing. The effect of the primary endodontic treatment and
extraction before early radiotherapy was examined.
Results: No specific complication, such as, post-extraction wound infection, radiation osteitis and osteoradionecrosis, were encountered despite the
early radiotherapy.
Conclusion: Based on the experimental study, a minimum 1-week waiting primary healing period for oral care before radiotherapy is suitable for
the early radiotherapy in head and neck cancer patients.