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Allergic reactions to hyaluronidase in pain management -A report of three cases-

Authors
 Tae Wan Kim  ;  Jae Hoon Lee  ;  Duck Mi Yoon  ;  Kyung Bong Yoon 
Citation
 Korean Journal of Anesthesiology, Vol.60(1) : 57-59, 2011 
Journal Title
 Korean Journal of Anesthesiology 
ISSN
 2005-6419 
Issue Date
2011
Abstract
Hyaluronidase has been gaining interest because it reduces tissue edema and fibrosis. Although rare, hyaluronidase has been shown to cause allergic reactions. A few cases of allergic reactions following hyaluronidase administration have been reported. Most of the described patients presented allergic reactions after peribulbar anesthesia for eye surgery. In this report, we describe three patients who experienced with allergic reactions to hyaluronidase following pain management. Two of the patients had a history of uneventful injection with hyaluronidase. All patients were afebrile and blood tests results were normal. Intradermal skin tests were positive. These clinical findings were helpful in establishing the differential diagnosis of infection. Although allergic reaction to hyaluronidase is rare and mostly benign, this must be considered before treating patients.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94344
DOI
10.4097/kjae.2011.60.1.57
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실)
Yonsei Authors
윤경봉(Yoon, Kyoung Bong) ; 윤덕미(Yoon, Duck Mi)
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