4 50

Cited 2 times in

Alteration of red blood cell aggregation during blood storage

Authors
 Hyun-Jung Lim ; Jeong-Hun Nam ; Sehyun Shin ; Jang-Soo Suh ; Byoung-Kwon Lee 
Citation
 Korea-Australia Rheology Journal, Vol.23(2) : 67~70, 2011 
Journal Title
 Korea-Australia Rheology Journal 
ISSN
 1226-119X 
Issue Date
2011
Abstract
Even though the trade-off between the benefits and risks of blood transfusion has been discussed for the last several decades, it requires further understanding of the rheological changes in stored blood that include the alteration of red blood cell (RBC) aggregation. The RBC aggregation of stored blood in its autologous plasma was monitored through the storage period (35 days). The critical shear stress, as a measure of RBC aggregation, was determined by using a microfluidic aggregometer. Blood was processed into a blood bag containing the anticoagulant CPDA1 and stored at 4°C. It was subjected to assays after zero, seven, 14, and 35 days. The critical shear stress for stored blood did not change up to 14 days of storage but exhibited a significant decrease after 35 days of storage. These results were identical to those of the conventional aggregation index (AI). Also, in the alteration of RBC aggregation for blood storage, the effect of the plasma factor was slightly stronger than that of the cellular factor. Through the present study, the critical shear stress as a new measure of RBC aggregation may help to monitor and control the quality of blood storage
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/94343
DOI
10.1007/s13367-011-0009-3
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
사서에게 알리기
  feedback
Link
 http://link.springer.com/article/10.1007%2Fs13367-011-0009-3#
Export
RIS (EndNote)
XLS (Excel)
XML

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse