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Respiratory syncytial virus prevention in children with congenital heart disease: who and how?

Authors
 Nam Kyun Kim  ;  Jae Young Choi 
Citation
 Korean Journal of Pediatrics, Vol.54(5) : 197-200, 2011 
Journal Title
Korean Journal of Pediatrics
ISSN
 1738-1061 
Issue Date
2011
Keywords
Respiratory syncytial virus ; Congenital heart defect ; Prevention ; Child
Abstract
Respiratory syncytial virus (RSV) is a major cause of respiratory infection in children. Most of the pediatric population have RSV infection before the age of 2, and recurrent infections are common even within one season. Chronic lung disease, prematurity, along with congenital heart disease (CHD) are major risk factors in severe lower respiratory infection. In hemo-dynamically significant CHD patients with RSV infection, hospitalization is usually needed and the possibility of treatment in intensive care unit and the use of mechanical ventilator support are known to increase. Therefore the prevention of RSV infection in CHD patients is mandatory. The current standard for RSV prevention is immunoprophylaxis by palivizumab. Immunoprophylaxis is recommended monthly in hemodynamically significant CHD patients, up to 5 months. Motabizumab, a second generation drug and newly developing RSV vaccines are also expected to play a key role in RSV prevention in the future. The prophylaxis of RSV infection in CHD patients is cost-effective in both the medical aspect of the patients as well as the socio-economic aspect. Therefore an effort to promote prevention should be made by not only the family of the patients but also by the government
Files in This Item:
T201103228.pdf Download
DOI
10.3345/kjp.2011.54.5.197
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Nam Kyun(김남균) ORCID logo https://orcid.org/0000-0001-6923-230X
Choi, Jae Young(최재영) ORCID logo https://orcid.org/0000-0002-1247-6669
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/94071
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