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Using 18F-FDG PET/CT to Detect an Occult Mesenchymal Tumor Causing Oncogenic Osteomalacia

 Hyo Jung Seo  ;  Yun Jung Choi  ;  Hyun Jeong Kim  ;  Yong Hyu Jeong  ;  Arthur Cho  ;  Jae Hoon Lee  ;  Mijin Yun  ;  Jong Doo Lee  ;  Won Jun Kang 
 Nuclear Medicine and Molecular Imaging (핵의학 분자영상), Vol.45(3) : 233-237, 2011 
Journal Title
 Nuclear Medicine and Molecular Imaging  (핵의학 분자영상) 
Issue Date
Oncogenic osteomalacia is a rare paraneoplastic syndrome characterized by renal phosphate excretion, hypophosphatemia, and osteomalacia. This syndrome is often caused by tumors of mesenchymal origin. Patients with oncogenic osteomalacia have abnormal bone mineralization, resulting in a high frequency of fractures. Tumor resection is the treatment of choice, as it will often correct the metabolic imbalance. Although oncogenic osteomalacia is a potentially curable disease, diagnosis is difficult and often delayed because of the small size and sporadic location of the tumor. Bone scintigraphy and radiography best characterize osteomalacia; magnetic resonance imaging findings are nonspecific. Here, we report a case of oncogenic osteomalacia secondary to a phosphaturic mesenchymal tumor that was successfully detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). This case illustrates the advantages of 18F-FDG PET/CT in detecting the occult mesenchymal tumor that causes oncogenic osteomalacia
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1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실) > 1. Journal Papers
Yonsei Authors
Kang, Won Jun(강원준) ORCID logo https://orcid.org/0000-0002-2107-8160
Yun, Mi Jin(윤미진) ORCID logo https://orcid.org/0000-0002-1712-163X
Lee, Jae Hoon(이재훈) ORCID logo https://orcid.org/0000-0002-9898-9886
Lee, Jong Doo(이종두)
Jeong, Yong Hyu(정용휴) ORCID logo https://orcid.org/0000-0002-0198-0026
Cho, Arthur Eung Hyuck(조응혁) ORCID logo https://orcid.org/0000-0001-8670-2473
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