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Using 18F-FDG PET/CT to Detect an Occult Mesenchymal Tumor Causing Oncogenic Osteomalacia

 Hyo Jung Seo  ;  Yun Jung Choi  ;  Hyun Jeong Kim  ;  Yong Hyu Jeong  ;  Arthur Cho  ;  Jae Hoon Lee  ;  Mijin Yun  ;  Jong Doo Lee  ;  Won Jun Kang 
 Nuclear Medicine and Molecular Imaging (핵의학 분자영상), Vol.45(3) : 233-237, 2011 
Journal Title
 Nuclear Medicine and Molecular Imaging  (핵의학 분자영상) 
Issue Date
Oncogenic osteomalacia is a rare paraneoplastic syndrome characterized by renal phosphate excretion, hypophosphatemia, and osteomalacia. This syndrome is often caused by tumors of mesenchymal origin. Patients with oncogenic osteomalacia have abnormal bone mineralization, resulting in a high frequency of fractures. Tumor resection is the treatment of choice, as it will often correct the metabolic imbalance. Although oncogenic osteomalacia is a potentially curable disease, diagnosis is difficult and often delayed because of the small size and sporadic location of the tumor. Bone scintigraphy and radiography best characterize osteomalacia; magnetic resonance imaging findings are nonspecific. Here, we report a case of oncogenic osteomalacia secondary to a phosphaturic mesenchymal tumor that was successfully detected by 18F-fluorodeoxyglucose positron emission tomography/computed tomography (18F-FDG PET/CT). This case illustrates the advantages of 18F-FDG PET/CT in detecting the occult mesenchymal tumor that causes oncogenic osteomalacia
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Nuclear Medicine (핵의학교실)
Yonsei Authors
강원준(Kang, Won Jun)
윤미진(Yun, Mi Jin) ORCID logo https://orcid.org/0000-0002-1712-163X
이재훈(Lee, Jae Hoon)
이종두(Lee, Jong Doo)
정용휴(Jeong, Yong Hyu) ORCID logo https://orcid.org/0000-0002-0198-0026
조응혁(Cho, Arthur Eung Hyuck) ORCID logo https://orcid.org/0000-0001-8670-2473
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