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내전형 연축성 발성장애 환자의 보툴리눔 독소-A 주입술 전후의 음성특성 비교
DC Field | Value | Language |
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dc.contributor.author | 김향희 | - |
dc.contributor.author | 최홍식 | - |
dc.date.accessioned | 2014-12-20T17:06:14Z | - |
dc.date.available | 2014-12-20T17:06:14Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 2092-5859 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93968 | - |
dc.description.abstract | Background and ObjectivesZZBotulinum toxin type A (BTX-A) injection is well known for its effectiveness in the treatment of “Spasmodic dysphonia”. However, studies on the efficacy of BTX-A injection have not been attempted in Korea. Therefore, this study was carried out to investigate the effects of BTX-A. Subjects and MethodZZThe study examined 12 female patients with ‘adductor spasmodic dysphonia’. Objective assesments included aerodynamic analysis and electoroglottography (EGG) of each patient before and after BTX-A. Subjective assessments included using the Korean-version of Voice Handicap Index-30 (KVHI-30) and a patient self-rating scale. ResultsZZAerodynamic analysis revealed that only maximum phonation time (MPT) was significantly shortened after the injection of BTX-A (p<0.05). In the EGG, the mean frequency distribution was significantly increased, while the mean amplitude and the mean closed quotient distribution were significantly decreased (p<0.05). The KVHI-30 and patient selfrating scale scores were significantly decreased (p<0.01) as well, demonstrating the effects of BTX-A on the quality of life. ConclusionZZOur results show the effects of BTX-A objectively by comparing voice characteristics, which were measured through EGG before and after BTX-A injection, as well as by determining aerodynamic characteristics. The subjective self-assessment on the quality of life is significant as it may serve as a clinically relevant measure. This study may be helpful in elucidating treatment efficacy of BTX-A in many ways. | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 148~153 | - |
dc.relation.isPartOf | Korean Journal of Otorhinolaryngology-Head and Neck Surgery | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | 내전형 연축성 발성장애 환자의 보툴리눔 독소-A 주입술 전후의 음성특성 비교 | - |
dc.title.alternative | Voice Characteristics of Adductor Spasmodic Dysphonia before and after Botulinum Toxin-A Injection | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Otorhinolaryngology (이비인후과학) | - |
dc.contributor.googleauthor | Boram Yun | - |
dc.contributor.googleauthor | Hyang Hee Kim | - |
dc.contributor.googleauthor | Yaelin Choi | - |
dc.contributor.googleauthor | Hong-Shik Choi | - |
dc.identifier.doi | 10.3342/kjorl-hns.2011.54.2.148 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A01107 | - |
dc.contributor.localId | A04223 | - |
dc.relation.journalcode | J02089 | - |
dc.subject.keyword | Spasmodic dysphonia | - |
dc.subject.keyword | Botulinum toxin | - |
dc.subject.keyword | Voice assessment | - |
dc.contributor.alternativeName | Kim, Hyang Hee | - |
dc.contributor.alternativeName | Choi, Hong Shik | - |
dc.contributor.affiliatedAuthor | Kim, Hyang Hee | - |
dc.contributor.affiliatedAuthor | Choi, Hong Shik | - |
dc.rights.accessRights | free | - |
dc.citation.volume | 54 | - |
dc.citation.number | 02 | - |
dc.citation.startPage | 148 | - |
dc.citation.endPage | 153 | - |
dc.identifier.bibliographicCitation | Korean Journal of Otorhinolaryngology-Head and Neck Surgery, Vol.54(02) : 148-153, 2011 | - |
dc.identifier.rimsid | 28583 | - |
dc.type.rims | ART | - |
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