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구강건조증에 대한 필로카핀 구강양치액의 효과

Other Titles
 Effect of Pilocarpine Mouthwash on Xerostomia 
Authors
 김지현  ;  박주현  ;  안형준  ;  권정승 
Citation
 Journal of Korean Academy of Oral Medicine (대한구강내과학회지), Vol.36(1) : 21-24, 2011 
Journal Title
 Journal of Korean Academy of Oral Medicine  (대한구강내과학회지) 
ISSN
 1225-0627 
Issue Date
2011
Abstract
Xerostomia is subjective feeling of dry mouth, a symptom that may or may not be accompanied by hyposalivation, an objective decrease in salivary flow. There are many causes induced xerostomia like drugs, salivary gland diseases, radiation therapy to the head and neck region, Sjögren syndrome, emotional stress etc. Insufficient salivary flow creates complications with oral candidiasis, dental caries, periodontitis, halitosis, dysgeusia. So finally, these complications lead to an overall decline in quality of life. Managements of xerostomia are eliminating or alterating the etiologic factors, relieving symptoms, preventing or correcting the consequences of salivary dysfunction, treating underlying disease and stimulating salivation. One of the salivation stimulation agents studied to treat xerostomia was the pilocarpine muscarinic agonist. Pilocarpine is one of salivation stimulants, a parasympathomimetic drug and non-selective muscarinic receptor agonist. Systemic pilocarpine has been used to stimulate salivary secretion. But systemic administration of pilocarpine has limitations such as increased risk of side effects and contraindications. Side effects of systemic pilocarpine administration are sweating, urinary and gastrointestinal disturbance, risk of cardiovascular and pulmonary disorders. This drug must be used carefully by patients with controlled asthma, chronic bronchitis, pulmonary or cardiac disease. Patient with acute asthma, narrow angle glaucoma, iritis should not use pilocarpine. Like this, systemic pilocarpine has many limitations. So, many investigators also have looked at the effectiveness of topical pilocarpine. Here we present patients with xerostomia which was relieved by pilocarpine mouthwash
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93662
Appears in Collections:
1. Journal Papers (연구논문) > 2. College of Dentistry (치과대학) > Dept. of Oral Medicine (구강내과학교실)
Yonsei Authors
권정승(Kwon, Jeong Seung) ; 박주현(Park, Ju Hyun) ; 안형준(Ahn, Hyoung Joon)
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