Cited 29 times in
Preparation of Interconnected Porous Chitosan Scaffolds by Sodium Acetate Particulate Leaching
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 신전수 | - |
dc.date.accessioned | 2014-12-20T16:52:20Z | - |
dc.date.available | 2014-12-20T16:52:20Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 0920-5063 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93538 | - |
dc.description.abstract | For tissue-engineering applications, a 3D porous chitosan scaffold was simply prepared from a mixture of acidic chitosan solution and sodium acetate particles as the porogen by a salt-leaching method. Differences in the porous structure in terms of pore morphology and interconnectivity between the salt-leached chitosan scaffold and phase-separated scaffold as the control were examined by using scanning electron microscopy, protein release and enzymatic degradation tests. A fibroblast (NIH-3T3) cell culture was performed for cell affinity evaluation. The chitosan scaffold prepared by salt-leaching showed good interconnectivity and improved mechanical properties. Furthermore, the chitosan scaffolds showed a high initial cell adhesion after 4 h cell culture and increased cell proliferation than the control. Thus, salt-leached chitosan scaffolds can be used for various tissue-engineering applications | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 1319~1329 | - |
dc.relation.isPartOf | JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Biocompatible Materials/chemistry | - |
dc.subject.MESH | Cell Adhesion/physiology | - |
dc.subject.MESH | Cell Proliferation/physiology | - |
dc.subject.MESH | Chitosan*/chemistry | - |
dc.subject.MESH | Materials Testing | - |
dc.subject.MESH | Mice | - |
dc.subject.MESH | Microscopy, Electrochemical, Scanning | - |
dc.subject.MESH | NIH 3T3 Cells | - |
dc.subject.MESH | Porosity | - |
dc.subject.MESH | Sodium Acetate/chemistry | - |
dc.subject.MESH | Tissue Engineering | - |
dc.subject.MESH | Tissue Scaffolds*/chemistry | - |
dc.title | Preparation of Interconnected Porous Chitosan Scaffolds by Sodium Acetate Particulate Leaching | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Microbiology (미생물학) | - |
dc.contributor.googleauthor | Jin Ik Lim | - |
dc.contributor.googleauthor | Yong-Keun Lee | - |
dc.contributor.googleauthor | Jeon-Soo Shin | - |
dc.contributor.googleauthor | Kook-Jin Lim | - |
dc.identifier.doi | 10.1163/092050610X504783 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02144 | - |
dc.relation.journalcode | J01261 | - |
dc.identifier.eissn | 1568-5624 | - |
dc.identifier.pmid | 20594410 | - |
dc.identifier.url | http://www.tandfonline.com/doi/abs/10.1163/092050610X504783 | - |
dc.subject.keyword | CHITOSAN SCAFFOLD | - |
dc.subject.keyword | POROUS STRUCTURE | - |
dc.subject.keyword | SALT-LEACHING | - |
dc.subject.keyword | TISSUE ENGINEERING | - |
dc.contributor.alternativeName | Shin, Jeon Soo | - |
dc.contributor.affiliatedAuthor | Shin, Jeon Soo | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 22 | - |
dc.citation.number | 10 | - |
dc.citation.startPage | 1319 | - |
dc.citation.endPage | 1329 | - |
dc.identifier.bibliographicCitation | JOURNAL OF BIOMATERIALS SCIENCE-POLYMER EDITION, Vol.22(10) : 1319-1329, 2011 | - |
dc.identifier.rimsid | 28293 | - |
dc.type.rims | ART | - |
Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.