344 540

Cited 64 times in

Determinants of perimacular inner retinal layer thickness in normal eyes measured by Fourier-domain optical coherence tomography.

DC Field Value Language
dc.contributor.author김나래-
dc.contributor.author김지현-
dc.contributor.author김찬윤-
dc.contributor.author성공제-
dc.contributor.author이은석-
dc.contributor.author이준원-
dc.date.accessioned2014-12-20T16:48:24Z-
dc.date.available2014-12-20T16:48:24Z-
dc.date.issued2011-
dc.identifier.issn0146-0404-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93413-
dc.description.abstractPURPOSE: To determine the effects of age, sex, spherical equivalent, axial length, anterior chamber depth, optic disc area, and central corneal thickness on perimacular inner retinal layer thickness in the normal human eye as measured by Fourier-domain optical coherence tomography (FD-OCT). METHODS: In this cross-sectional observational study, 182 Korean healthy subjects aged from 22 to 84 years were included. To obtain the inner retinal layer thickness, perimacular ganglion cell complex thickness, which extends from the internal limiting membrane to the inner nuclear layer, was measured by FD-OCT on one randomly selected eye of each subject. Linear regression analyses of the effects of demographic and clinical variables, including age, sex, spherical equivalent, axial length, anterior chamber depth, optic disc area, and central corneal thickness, on perimacular inner retinal layer thickness were performed. RESULTS: The mean inner retinal layer thickness for the entire population was 93.87 μm. Thinner inner retinal layer measurements were associated with older age (P = 0.010) and greater axial length (P = 0.021). Mean inner retinal layer thickness decreased by approximately 1.59 μm for every decade of age and by approximately 1.56 μm for every 1-mm greater axial length. There was no relationship between inner retinal layer thickness and sex, anterior chamber depth, optic disc area, or central corneal thickness. CONCLUSIONS: Inner retinal layer thickness, as measured by FD-OCT, varies significantly with age and axial length. The effect is small but clinically relevant in the interpretation of inner retinal layer thickness measurements.-
dc.description.statementOfResponsibilityopen-
dc.formatapplication/pdf-
dc.relation.isPartOfINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHAging/physiology*-
dc.subject.MESHAnterior Chamber/anatomy & histology-
dc.subject.MESHAxial Length, Eye/anatomy & histology*-
dc.subject.MESHCornea/anatomy & histology-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHFourier Analysis-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHOptic Disk/anatomy & histology-
dc.subject.MESHReference Values-
dc.subject.MESHRetina/anatomy & histology-
dc.subject.MESHRetinal Ganglion Cells/cytology*-
dc.subject.MESHRetinal Photoreceptor Cell Inner Segment*-
dc.subject.MESHSex Factors-
dc.subject.MESHTomography, Optical Coherence*-
dc.subject.MESHYoung Adult-
dc.titleDeterminants of perimacular inner retinal layer thickness in normal eyes measured by Fourier-domain optical coherence tomography.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorNa Rae Kim-
dc.contributor.googleauthorJi Hyun Kim-
dc.contributor.googleauthorJunwon Lee-
dc.contributor.googleauthorEun Suk Lee-
dc.contributor.googleauthorGong Je Seong-
dc.contributor.googleauthorChan Yun Kim-
dc.identifier.doi10.1167/iovs.10-6648-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00998-
dc.contributor.localIdA03036-
dc.contributor.localIdA00347-
dc.contributor.localIdA01035-
dc.contributor.localIdA01946-
dc.relation.journalcodeJ01187-
dc.identifier.eissn1552-5783-
dc.identifier.pmid21357406-
dc.contributor.alternativeNameKim, Na Rae-
dc.contributor.alternativeNameKim, Ji Hyun-
dc.contributor.alternativeNameKim, Chan Yun-
dc.contributor.alternativeNameSeong, Gong Je-
dc.contributor.alternativeNameLee, Eun Suk-
dc.contributor.affiliatedAuthorKim, Ji Hyun-
dc.contributor.affiliatedAuthorLee, Eun Suk-
dc.contributor.affiliatedAuthorKim, Na Rae-
dc.contributor.affiliatedAuthorKim, Chan Yun-
dc.contributor.affiliatedAuthorSeong, Gong Je-
dc.rights.accessRightsfree-
dc.citation.volume52-
dc.citation.number6-
dc.citation.startPage3413-
dc.citation.endPage3418-
dc.identifier.bibliographicCitationINVESTIGATIVE OPHTHALMOLOGY & VISUAL SCIENCE, Vol.52(6) : 3413-3418, 2011-
dc.identifier.rimsid27644-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.