Cited 7 times in
Enhanced cellular responses of vascular endothelial cells on poly-γ-glutamic acid/PU composite film treated with microwave-induced plasma at atmospheric pressure
DC Field | Value | Language |
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dc.contributor.author | 강재경 | - |
dc.contributor.author | 권병주 | - |
dc.contributor.author | 박종철 | - |
dc.contributor.author | 이미희 | - |
dc.contributor.author | 한인호 | - |
dc.date.accessioned | 2014-12-20T16:48:14Z | - |
dc.date.available | 2014-12-20T16:48:14Z | - |
dc.date.issued | 2011 | - |
dc.identifier.issn | 1598-5032 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/93408 | - |
dc.description.abstract | Poly-γ-glutamic acid (γ-PGA), which is produced by microbial fermentation, is a biodegradable, hydrophilic and non-toxic biomaterial. γ-PGA has many carboxyl groups that makes it a polyanionic biopolymer with swelling ability, biocompatibility and anticoagulant activity. On the other hand, few studies have examined the effect of γ-PGA on the cellular activity of human umbilical vein endothelial cells (HUVECs). The present study evaluated the effects of γ-PGA and fabricated γ-PGA/PU composite films on the attachment and proliferation of HUVECs after treatment with microwave plasma at atmospheric pressure. The results confirmed that γ-PGA is capable of increasing the proliferation and differentiation of HUVECs to form capillary tubes with enhanced alignment and organization. Moreover, the microwave plasma modified γ-PGA/PU composite film was more hydrophilic and the surface roughness was enhanced. In addition, the attachment and proliferation of the HUVECs were increased by the plasma treatment. These results suggest that γ-PGA and surface modified γ-PGA/PU composite can be applied as bioactive and biocompatible materials in vascular tissue engineering but further testing of γ-PGA and γ-PGA/PU composite films will be needed to confirm the potential effects for use in vascular applications | - |
dc.description.statementOfResponsibility | open | - |
dc.format.extent | 537~541 | - |
dc.relation.isPartOf | MACROMOLECULAR RESEARCH | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.title | Enhanced cellular responses of vascular endothelial cells on poly-γ-glutamic acid/PU composite film treated with microwave-induced plasma at atmospheric pressure | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학) | - |
dc.contributor.googleauthor | Bong Joo Park | - |
dc.contributor.googleauthor | Byoung Ju Kwon | - |
dc.contributor.googleauthor | Jae Kyeong Kang | - |
dc.contributor.googleauthor | Mi Hee Lee | - |
dc.contributor.googleauthor | Inho Han | - |
dc.contributor.googleauthor | Jeong Koo Kim | - |
dc.contributor.googleauthor | Jong-Chul Park | - |
dc.identifier.doi | 10.1007/s13233-011-0605-6 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00076 | - |
dc.contributor.localId | A00218 | - |
dc.contributor.localId | A01662 | - |
dc.contributor.localId | A04317 | - |
dc.contributor.localId | A02777 | - |
dc.relation.journalcode | J02177 | - |
dc.identifier.eissn | 2092-7673 | - |
dc.identifier.url | http://link.springer.com/article/10.1007%2Fs13233-011-0605-6# | - |
dc.subject.keyword | poly-γ-glutamic acid | - |
dc.subject.keyword | polyurethane | - |
dc.subject.keyword | human umbilical vein endothelial cells | - |
dc.subject.keyword | microwave-induced argon plasma | - |
dc.contributor.alternativeName | Kang, Jae Kyeong | - |
dc.contributor.alternativeName | Kwon, Byeong Ju | - |
dc.contributor.alternativeName | Park, Jong Chul | - |
dc.contributor.alternativeName | Lee, Mi Hee | - |
dc.contributor.alternativeName | Han, In Ho | - |
dc.contributor.affiliatedAuthor | Kang, Jae Kyeong | - |
dc.contributor.affiliatedAuthor | Kwon, Byeong Ju | - |
dc.contributor.affiliatedAuthor | Park, Jong Chul | - |
dc.contributor.affiliatedAuthor | Han, In Ho | - |
dc.contributor.affiliatedAuthor | Lee, Mi Hee | - |
dc.rights.accessRights | not free | - |
dc.citation.volume | 19 | - |
dc.citation.number | 6 | - |
dc.citation.startPage | 537 | - |
dc.citation.endPage | 541 | - |
dc.identifier.bibliographicCitation | MACROMOLECULAR RESEARCH, Vol.19(6) : 537-541, 2011 | - |
dc.identifier.rimsid | 27640 | - |
dc.type.rims | ART | - |
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