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Effect of zoledronic acid on acro-osteolysis and osteoporosis in a patient with Hajdu-Cheney syndrome

Authors
 Sena Hwang  ;  Dong Yoeb Shin  ;  Seong Hwan Moon  ;  Eun Jig Lee  ;  Sung-Kil Lim  ;  Ok Hwa Kim  ;  Yumie Rhee 
Citation
 YONSEI MEDICAL JOURNAL, Vol.52(3) : 543-546, 2011 
Journal Title
YONSEI MEDICAL JOURNAL
ISSN
 0513-5796 
Issue Date
2011
MeSH
Acro-Osteolysis/complications ; Acro-Osteolysis/drug therapy* ; Adult ; Bone Density Conservation Agents/therapeutic use* ; Diphosphonates/therapeutic use* ; Female ; Hajdu-Cheney Syndrome/complications ; Hajdu-Cheney Syndrome/drug therapy* ; Humans ; Imidazoles/therapeutic use* ; Osteoporosis/complications ; Osteoporosis/drug therapy*
Keywords
Hajdu-Cheney Syndrome ; osteoporosis ; zoledronic acid
Abstract
Hajdu-Cheney syndrome is a rare, autosomal dominant skeletal dysplasia marked by acro-osteolysis of the distal phalanges and severe osteoporosis. Although there are more than 60 reports published to date, proper treatment and subsequent outcome have been scarce. Herein, we report a progress of anti-resorptive therapy with zoledronic acid, in a woman with Hajdu-Cheney syndrome. Results suggest that anti-resorptive therapy may be important in delaying the progress of osteoporosis and preventing fractures, but not necessarily acro-osteolysis itself
Files in This Item:
T201101240.pdf Download
DOI
10.3349/ymj.2011.52.3.543
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Seong Hwan(문성환)
Shin, Dong Yeob(신동엽) ORCID logo https://orcid.org/0000-0003-1048-7978
Rhee, Yumie(이유미) ORCID logo https://orcid.org/0000-0003-4227-5638
Lee, Eun Jig(이은직) ORCID logo https://orcid.org/0000-0002-9876-8370
Lim, Sung Kil(임승길)
Hwang, Se Na(황세나)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/93158
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