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Predictors of stent fracture in patients treated with closed-cell design stents: sirolimus-eluting stent and its bare-metal counterpart, the BX velocity stent

 Sang Min Park  ;  Jong-Youn Kim  ;  Bum-Kee Hong  ;  Byoung Kwon Lee  ;  Pil-Ki Min  ;  Sejoong Rim  ;  Hee-Sun Mun  ;  Sung Woo Kwon  ;  Sung-Joo Lee  ;  Jong Kwan Park  ;  Hyuck Moon Kwon 
 CORONARY ARTERY DISEASE, Vol.22(1) : 40-44, 2011 
Journal Title
Issue Date
Aged ; Angioplasty, Balloon, Coronary/instrumentation* ; Comparative Effectiveness Research ; Coronary Angiography ; Coronary Stenosis/diagnosis ; Coronary Stenosis/diagnostic imaging ; Coronary Stenosis/physiopathology ; Coronary Stenosis/therapy* ; Coronary Vessels/pathology* ; Drug-Eluting Stents/adverse effects* ; Drug-Eluting Stents/standards ; Equipment Failure Analysis ; Female ; Humans ; Immunosuppressive Agents/pharmacology ; Male ; Middle Aged ; Plaque, Atherosclerotic/diagnosis ; Plaque, Atherosclerotic/physiopathology* ; Risk Factors ; Sirolimus/pharmacology ; Treatment Outcome
coronary artery ; drug-eluting stent ; stent fracture
OBJECTIVE: The aim of this study was to evaluate the predictors of coronary stent fracture in patients treated with closed-cell design stents including the sirolimus-eluting stent (SES) and its bare-metal platform, Bx velocity stent (BVS).

BACKGROUND: Various mechanical factors have been considered to be the predictors of stent fracture, especially in patients treated with SES. However, it is unknown whether SES is more prone to fracture compared with BVS.

METHODS: We retrospectively analyzed 391 lesions treated with SES or BVS in 339 patients who underwent follow-up coronary angiography.

RESULTS: A total of 30 stent fractures (7.7%) in 28 patients treated with 29 SES (96.7%) and one BVS (3.3%) was found. On univariate analyses, stent fracture was related to angulated lesions (>45°) during diastole, longer stent, larger number of stents per lesion (P<0.001), right coronary artery (RCA) placement (P=0.008), and SES (P=0.016). On multivariate analyses, however, angulated lesion (odds ratio: 6.73; 95% confidence interval: 2.71-16.71; P<0.001) and RCA placement (odds ratio: 2.82; 95% confidence interval: 1.03-7.72; P=0.044) served as independent predictors of stent fracture while SES (P=0.080) and total stent length (P=0.069) showed only trends that did not reach statistical significance.

CONCLUSIONS: This study showed that fracture of SES or BVS with the same closed-cell design platform was related to angulated lesion and RCA placement, but SES itself was not an independent predictor of stent fracture.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kwon, Sung Woo(권성우)
Kwon, Hyuck Moon(권혁문) ORCID logo https://orcid.org/0000-0001-9901-5015
Kim, Jong Youn(김종윤) ORCID logo https://orcid.org/0000-0001-7040-8771
Mun, Hee Sun(문희선)
Min, Pil Ki(민필기) ORCID logo https://orcid.org/0000-0001-7033-7651
Lee, Byoung Kwon(이병권) ORCID logo https://orcid.org/0000-0001-9259-2776
Rim, Se Joong(임세중) ORCID logo https://orcid.org/0000-0002-7631-5581
Hong, Bum Kee(홍범기) ORCID logo https://orcid.org/0000-0002-6456-0184
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