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Predictors of stent fracture in patients treated with closed-cell design stents: sirolimus-eluting stent and its bare-metal counterpart, the BX velocity stent

 Sang Min Park  ;  Jong-Youn Kim  ;  Hyuck Moon Kwon  ;  Jong Kwan Park  ;  Sung-Joo Lee  ;  Sung Woo Kwon  ;  Hee-Sun Mun  ;  Sejoong Rim  ;  Pil-Ki Min  ;  Byoung Kwon Lee  ;  Bum-Kee Hong 
 Coronary Artery Disease, Vol.22(1) : 40-44, 2011 
Journal Title
 Coronary Artery Disease 
Issue Date
OBJECTIVE: The aim of this study was to evaluate the predictors of coronary stent fracture in patients treated with closed-cell design stents including the sirolimus-eluting stent (SES) and its bare-metal platform, Bx velocity stent (BVS). BACKGROUND: Various mechanical factors have been considered to be the predictors of stent fracture, especially in patients treated with SES. However, it is unknown whether SES is more prone to fracture compared with BVS. METHODS: We retrospectively analyzed 391 lesions treated with SES or BVS in 339 patients who underwent follow-up coronary angiography. RESULTS: A total of 30 stent fractures (7.7%) in 28 patients treated with 29 SES (96.7%) and one BVS (3.3%) was found. On univariate analyses, stent fracture was related to angulated lesions (>45°) during diastole, longer stent, larger number of stents per lesion (P<0.001), right coronary artery (RCA) placement (P=0.008), and SES (P=0.016). On multivariate analyses, however, angulated lesion (odds ratio: 6.73; 95% confidence interval: 2.71-16.71; P<0.001) and RCA placement (odds ratio: 2.82; 95% confidence interval: 1.03-7.72; P=0.044) served as independent predictors of stent fracture while SES (P=0.080) and total stent length (P=0.069) showed only trends that did not reach statistical significance. CONCLUSIONS: This study showed that fracture of SES or BVS with the same closed-cell design platform was related to angulated lesion and RCA placement, but SES itself was not an independent predictor of stent fracture.
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1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
권성우(Kwon, Sung Woo) ; 권혁문(Kwon, Hyuck Moon) ; 김종윤(Kim, Jong Youn) ; 문희선(Mun, Hee Sun) ; 민필기(Min, Pil Ki) ; 이병권(Lee, Byoung Kwon) ; 임세중(Rim, Se Joong) ; 홍범기(Hong, Bum Kee)
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