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Mucous membrane pemphigoid with immunoglobulin G autoantibodies against full-length and 120-kDa ectodomain of BP180

Authors
 Yuri CHOI ; Sang Eun LEE ; Soo-Chan KIM ; Takashi HASHIMOTO ; Shunpei FUKUDA 
Citation
 Journal of Dermatology, Vol.38(2) : 169~172, 2011 
Journal Title
 Journal of Dermatology 
ISSN
 0385-2407 
Issue Date
2011
Abstract
Mucous membrane pemphigoid (MMP) is a rare autoimmune, subepidermal, bullous disease characterized by erosive lesions on the mucous membranes and skin. MMP reacts with various target antigens including BP180, laminin-332, β4 integrin, α6 integrin or type VII collagen. We present a 67-year-old male MMP patient who had lesions on the oral and ocular mucous membranes and facial skin. By immunoblot analyses, immunoglobulin G autoantibodies in the patient's sera reacted with full-length BP180 and the 120-kDa ectodomain of BP180 (LAD-1).
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/93116
DOI
10.1111/j.1346-8138.2010.01072.x
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Dermatology
Yonsei Authors
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Link
 http://onlinelibrary.wiley.com/doi/10.1111/j.1346-8138.2010.01072.x/abstract
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