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Sex differences in the relationship between leukocyte count and chronic kidney disease: the 2007 Korean National Health and Nutrition Examination Survey

DC Field Value Language
dc.contributor.author나하영-
dc.contributor.author박병진-
dc.contributor.author심재용-
dc.contributor.author이용제-
dc.contributor.author이혜리-
dc.contributor.author정동혁-
dc.date.accessioned2014-12-20T16:38:58Z-
dc.date.available2014-12-20T16:38:58Z-
dc.date.issued2011-
dc.identifier.issn1540-9996-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/93114-
dc.description.abstractBACKGROUND: Chronic kidney disease (CKD) has emerged as an independent predictor for cardiovascular disease (CVD), which is now regarded as an inflammatory disease. This study aimed to determine the association of CKD with white blood cell (WBC) count as a marker of systemic inflammation. METHODS: We examined the association of WBC count with CKD in 2825 Korean adults (1155 men, 1670 women) in the 2007 Korean National Health and Nutrition Examination Survey (KNHANES). CKD was defined as either proteinuria or a glomerular filtration rate (GFR) <60 mL/min/1.73 m(2). The odds ratios (ORs) for CKD were calculated using multivariate logistic regression analysis after adjusting for confounding variables across gender-specific WBC count quartiles. RESULTS: The proportion of CKD increased with increasing WBC quartiles, from 9.7% in the lowest quartile to 20.7% in the highest quartile for women. In multivariate logistic regression analysis, the corresponding odds ratios (95% confidence intervals [CIs]) for a CKD across WBC count quartiles among women were 1.00, 1.45 (0.91-2.31), 1.65 (1.03-2.63), and 2.11 (1.33-3.35), after adjusting for age, body mass index (BMI), systolic blood pressure, fasting plasma glucose, smoking status, current drinking high-density lipoprotein cholesterol (HDL-C), and triglyceride. In contrast, compared with women, men appeared to have no significant results of a relationship between WBC quartiles and CKD. CONCLUSIONS: Our study shows a significant association between WBC count and the risk for CKD in women. Accordingly, potential health benefits of early detection of a higher level of WBC count may be useful for CKD risk assessment in women.-
dc.description.statementOfResponsibilityopen-
dc.format.extent99~105-
dc.relation.isPartOfJOURNAL OF WOMENS HEALTH-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAlcohol Drinking/epidemiology-
dc.subject.MESHAlcohol Drinking/psychology-
dc.subject.MESHBiomarkers-
dc.subject.MESHBlood Pressure/physiology-
dc.subject.MESHBody Mass Index-
dc.subject.MESHCholesterol/blood-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFemale-
dc.subject.MESHGlomerular Filtration Rate/physiology-
dc.subject.MESHHealth Knowledge, Attitudes, Practice*-
dc.subject.MESHHumans-
dc.subject.MESHKorea/epidemiology-
dc.subject.MESHLeukocyte Count*-
dc.subject.MESHLogistic Models-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNational Health Programs-
dc.subject.MESHNutrition Surveys-
dc.subject.MESHProteinuria/physiopathology-
dc.subject.MESHRenal Insufficiency, Chronic/epidemiology*-
dc.subject.MESHSmoking/epidemiology-
dc.subject.MESHSmoking/psychology-
dc.subject.MESHSurveys and Questionnaires-
dc.titleSex differences in the relationship between leukocyte count and chronic kidney disease: the 2007 Korean National Health and Nutrition Examination Survey-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학)-
dc.contributor.googleauthorHa-Young Na-
dc.contributor.googleauthorJae-Yong Shim-
dc.contributor.googleauthorHye-Ree Lee-
dc.contributor.googleauthorDong-Hyuk Jung-
dc.contributor.googleauthorHong-Bae Kim-
dc.contributor.googleauthorByoung-Jin Park-
dc.contributor.googleauthorRae-Jun Jung-
dc.contributor.googleauthorYong-Jae Lee-
dc.identifier.doi10.1089/jwh.2010.2115-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01236-
dc.contributor.localIdA01477-
dc.contributor.localIdA02207-
dc.contributor.localIdA02982-
dc.contributor.localIdA03595-
dc.contributor.localIdA03310-
dc.relation.journalcodeJ01933-
dc.identifier.eissn1931-843X-
dc.identifier.pmid21194272-
dc.identifier.urlhttp://online.liebertpub.com/doi/abs/10.1089/jwh.2010.2115-
dc.contributor.alternativeNameNa, Ha Young-
dc.contributor.alternativeNamePark, Byoung Jin-
dc.contributor.alternativeNameShim, Jae Yong-
dc.contributor.alternativeNameLee, Yong Jae-
dc.contributor.alternativeNameLee, Hye Ree-
dc.contributor.alternativeNameJung, Dong Hyuk-
dc.contributor.affiliatedAuthorNa, Ha Young-
dc.contributor.affiliatedAuthorPark, Byoung Jin-
dc.contributor.affiliatedAuthorShim, Jae Yong-
dc.contributor.affiliatedAuthorLee, Yong Jae-
dc.contributor.affiliatedAuthorJung, Dong Hyuk-
dc.contributor.affiliatedAuthorLee, Hye Ree-
dc.rights.accessRightsnot free-
dc.citation.volume20-
dc.citation.number1-
dc.citation.startPage99-
dc.citation.endPage105-
dc.identifier.bibliographicCitationJOURNAL OF WOMENS HEALTH, Vol.20(1) : 99-105, 2011-
dc.identifier.rimsid28037-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers

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