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Relationship of neutrophil-lymphocyte ratio with arterial stiffness and coronary calcium score

DC FieldValueLanguage
dc.contributor.author나하영-
dc.contributor.author박병진-
dc.contributor.author심재용-
dc.contributor.author이용제-
dc.contributor.author이혜리-
dc.contributor.author정동혁-
dc.date.accessioned2014-12-20T16:29:24Z-
dc.date.available2014-12-20T16:29:24Z-
dc.date.issued2011-
dc.identifier.issn0009-8981-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/92812-
dc.description.abstractBACKGROUND: Emerging evidence suggests that the neutrophil/lymphocyte ratio (NLR) may be a useful marker of cardiovascular disease and a more powerful predictor than any other leukocyte subtypes. We determined whether NLR is related to atherosclerosis measured by brachial-ankle pulse wave velocity (baPWV) and coronary calcium score (CCS). METHODS: We examined the relationship of NLR with baPWV and CCS in 849 Korean adults in a health examination program. The odds ratios for a high baPWV or a high CCS were calculated using multivariate logistic regression analysis across NLR quartiles. A high baPWV was defined as >1500 cm/s (>75th percentile) and a high CCS was defined as over 100 (at least moderate atherosclerotic plaque burden). RESULTS: The ORs (95% CIs) for a high baPWV by NLR quartiles were 1.00, 0.76 (0.41-1.39), 1.08 (0.61-1.90), and 2.12 (1.18-3.83) after adjusting for confounding variables. Similarly, positive associations between NLR and a high CCS were also observed after adjusting for the same co-variables. CONCLUSION: A higher NLR was independently associated with arterial stiffness and CCS. Accordingly, a higher NLR may be a useful additional measure in assessing cardiovascular risks in clinical practice.-
dc.description.statementOfResponsibilityopen-
dc.format.extent925~929-
dc.relation.isPartOfClinica Chimica Acta-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleRelationship of neutrophil-lymphocyte ratio with arterial stiffness and coronary calcium score-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Family Medicine (가정의학)-
dc.contributor.googleauthorByoung-Jin Park-
dc.contributor.googleauthorJae-Yong Shim-
dc.contributor.googleauthorYong-Jae Lee-
dc.contributor.googleauthorHa-Young Na-
dc.contributor.googleauthorHong-Bae Kim-
dc.contributor.googleauthorDong-Hyuk Jung-
dc.contributor.googleauthorJung-Hyun Lee-
dc.contributor.googleauthorHye-Ree Lee-
dc.identifier.doi10.1016/j.cca.2011.01.021-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.relation.journalcodeJ00543-
dc.identifier.urlhttp://www.sciencedirect.com/science/article/pii/S0009898111000301-
dc.contributor.alternativeNameNa, Ha Young-
dc.contributor.alternativeNamePark, Byoung Jin-
dc.contributor.alternativeNameShim, Jae Yong-
dc.contributor.alternativeNameLee, Yong Jae-
dc.contributor.alternativeNameLee, Hye Ree-
dc.contributor.alternativeNameJung, Dong Hyuk-
dc.identifier.localIdT201100854-
dc.rights.accessRightsnot free-
dc.citation.volume412-
dc.citation.number11-12-
dc.citation.startPage925-
dc.citation.endPage929-
dc.identifier.bibliographicCitationClinica Chimica Acta, Vol.412(11-12) : 925-929, 2011-
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실)

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