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Relation of inflammation and left atrial remodeling in atrial fibrillation occurring in early phase of acute myocardial infarction.

Authors
 Hye Jin Hwang  ;  Jong-Won Ha  ;  Boyoung Joung  ;  Eun-Hee Choi  ;  Jaedeok Kim  ;  Min-Soo Ahn  ;  Moon-Hyoung Lee  ;  Yangsoo Jang  ;  Namsik Chung  ;  Sung Soon Kim 
Citation
 International Journal of Cardiology, Vol.146(1) : 28-31, 2011 
Journal Title
 International Journal of Cardiology 
ISSN
 0167-5273 
Issue Date
2011
Abstract
BACKGROUND: Inflammation is frequently associated with the development of atrial fibrillation (AF). This study was performed to investigate whether the high sensitivity C-reactive protein (hsCRP) present during acute inflammation could predict early AF and its relationship to left atrial (LA) enlargement in acute myocardial infarction (AMI). METHODS AND RESULTS: In 401 consecutive AMI patients, AF predictors were compared between those with and without early AF. Early AF was defined as AF developing within 24 h after AMI. In order to identify the difference in the AF predictors according to LA enlargement, patients were subgrouped according to an LA volume index (LAVI) of <32 cm(3)/m(2) (group 1, n=321) and ≥32 cm(3)/m(2) (group 2, n=80). Thirty-three (8.2%) patients developed early AF including 17 (5.3%) and 16 (20%) patients in groups 1 and 2, respectively. The independent predictors of AF were multivessel involvement (OR=2.51, p=0.03), LAVI≥32 cm(3)/m(2) (OR=2.47, p=0.03), higher hsCRP (OR=2.24, p=0.05), and old age (OR=1.06, p=0.01) in all patients. In the subgroups divided by the LAVI, higher hsCRP was a predictor of early AF only in group 1 (OR=4.56, p=0.004). CONCLUSIONS: Our results suggest that multivessel involvement, enlarged LA, higher hsCRP, and old age are predictors of early AF after AMI. However, hsCRP could be strongly related to early AF only in AMI patients with less dilated LA.
Full Text
http://www.sciencedirect.com/science/article/pii/S0167527309006470
DOI
10.1016/j.ijcard.2009.05.065
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Biomedical Systems Informatics (의생명시스템정보학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Sung Soon(김성순)
Kim, Jae Deok(김재덕)
Lee, Moon Hyoung(이문형) ORCID logo https://orcid.org/0000-0002-7268-0741
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Chung, Nam Sik(정남식)
Joung, Bo Young(정보영) ORCID logo https://orcid.org/0000-0001-9036-7225
Choi, Eun Hee(최은희)
Ha, Jong Won(하종원) ORCID logo https://orcid.org/0000-0002-8260-2958
Hwang, Hye Jin(황혜진)
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92654
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