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크론병 환자에서 Infliximab 치료 후 발생한 중증 다발성 결핵 1예

Other Titles
 A Case of Multiple Tuberculosis Associated with Infliximab Therapy in Crohn's Disease. 
Authors
 김희욱 ; 장성일 ; 이상인 ; 박효진 ; 변민광 ; 윤영훈 ; 김번 
Citation
 대한내과학회지, Vol.83(3) : 337~341, 2012 
Journal Title
 대한내과학회지 
ISSN
 1226-329X 
Issue Date
2012
Abstract
Infliximab, a tumor necrosis factor-alpha (TNF-alpha) inhibitor, has been approved for the treatment of a variety of inflammatory illnesses, including Crohn's disease. However, infliximab can increase the risk of reactivation of latent tuberculosis (Tbc) infection by affecting host immune responses. Therefore, a screening test should be performed before the initiation of infliximab therapy, and patients with evidence of latent infection should be treated with prophylactic anti-Tbc therapy. Here, we report a case of multifocal disseminated tuberculosis after treatment with infliximab in a patient diagnosed with Crohn's disease who had no past history of Tbc and showed a negative screening test.
URI
http://ir.ymlib.yonsei.ac.kr/handle/22282913/92236
Appears in Collections:
1. 연구논문 > 1. College of Medicine > Dept. of Internal Medicine
Yonsei Authors
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Link
 http://www.ekjm.org/journal/view.php?number=23029
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