326 484

Cited 0 times in

구강 편평세포암종에서 정상 구강점막으로부터 암종으로의 이행 부위에 대한 조직학적 유형 분석

Other Titles
 Analysis of Histopathological Types of the Transitional Area from Normal Oral Mucosa to Squamous Cell Carcinoma 
 한선희  ;  김진 
 Korean Journal of Oral and Maxillofacial Pathology, Vol.36(1) : 1-6, 2012 
Journal Title
Korean Journal of Oral and Maxillofacial Pathology(대한구강악안면병리학회지)
Issue Date
Dysplasia ; Oral squamous cell carcinoma ; Transitional area
Oral squamous cell carcinoma (OSCC) develops through multistep process, that is, from normal mucosa to hyperplastic area and progressed to dysplasia, carcinoma in situ, and finally to invasive carcinoma. The purpose of this study is to investigate the histological types of the transitional area from normal oral mucosa to invasive carcinoma for the baseline data to search intermediate end point markers for early detection of OSCC. For this purpose, we reviewed the 85 patients who were diagnosed as OSCC in the Department of Oral Pathology, Yonsei University College of Dentistry, from 2002 to 2008. We classified these histopathologic findings by light-microscopy, according to the histologic pattern of transitional areas. As results, stepwise transformation from normal oral mucosa, to dysplasia and to OSCC was shown in 47 patients. Intermittent lesions were seen in 16 patients, in which normal oral mucosa, dysplasia, and OSCC were alternately arranged. Twenty two patients showed abruptly transformed to OSCC from normal oral mucosa. These preliminary data will be used for searching biomarkers for early detection of OSCC.
Files in This Item:
T201200700.pdf Download
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Oral Pathology (구강병리학교실) > 1. Journal Papers
Yonsei Authors
Kim, Jin(김진)
사서에게 알리기


Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.