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Syndrome of inappropriate antidiuretic hormone secretion in a patient with large cell neuroendocrine carcinoma

Authors
 Hyung Jung Oh  ;  Mi Jung Lee  ;  Seon Jung Jang  ;  Dong Ho Shin  ;  Shin-Wook Kang 
Citation
 YONSEI MEDICAL JOURNAL, Vol.53(3) : 667-669, 2012 
Journal Title
 YONSEI MEDICAL JOURNAL 
ISSN
 0513-5796 
Issue Date
2012
MeSH
Carcinoma, Large Cell/pathology* ; Carcinoma, Neuroendocrine/pathology* ; Humans ; Inappropriate ADH Syndrome/pathology* ; Male ; Middle Aged
Keywords
Hyponatremia ; syndrome of inappropriate antidiuresis ; large cell neuroendocrine carcinoma
Abstract
The syndrome of inappropriate antidiuretic hormone secretion has only been reported in a few patients with large cell neuroendocrine carcinoma (LCNEC); however, it has never been reported in a patient with LCNEC of the lung, whose serum sodium levels were normalized after surgical resection of the mass. A 63-year-old male presented with a two-day history of dizziness and recent memory loss. On admission, his serum sodium level was 113 mEq/L with a serum osmolality of 236 mosm/kg, a urine osmolality of 441 mosm/kg, and a urine sodium level of 65 mEq/L. His chest computed tomography revealed a 2.7×2.3 cm-sized mass in the left lower lobe. After surgical removal of the mass, his serum sodium concentrations were normalized, and histopathology of the mass revealed LCNEC.
Files in This Item:
T201201188.pdf Download
DOI
22477016
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kang, Shin Wook(강신욱) ORCID logo https://orcid.org/0000-0002-5677-4756
Oh, Hyung Jung(오형중)
Lee, Mi Jung(이미정)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/92084
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