Cited 48 times in
Phagocytosis and endocytosis of silver nanoparticles induce interleukin-8 production in human macrophages
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 최인홍 | - |
dc.date.accessioned | 2014-12-19T17:48:02Z | - |
dc.date.available | 2014-12-19T17:48:02Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0513-5796 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/92083 | - |
dc.description.abstract | Phagocytosis or endocytosis by macrophages is critical to the uptake of fine particles, including nanoparticles, in order to initiate toxic effects in cells. Here, our data enhance the understanding of the process of internalization of silver nanoparticles by macrophages. When macrophages were pre-treated with inhibitors to phagocytosis, caveolin-mediated endocytosis, or clathrin-mediated endocytosis, prior to exposure to silver nanoparticles, Interleukin-8 (IL-8) production was inhibited. Although cell death was not reduced, the inflammatory response by macrophages was compromised by phagocytosis and endocytosis inhibitors. | - |
dc.description.statementOfResponsibility | open | - |
dc.format | application/pdf | - |
dc.relation.isPartOf | YONSEI MEDICAL JOURNAL | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Cell Line | - |
dc.subject.MESH | Cell Survival/drug effects | - |
dc.subject.MESH | Endocytosis/physiology* | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Interleukin-8/metabolism* | - |
dc.subject.MESH | Macrophages/drug effects | - |
dc.subject.MESH | Macrophages/metabolism* | - |
dc.subject.MESH | Metal Nanoparticles/chemistry* | - |
dc.subject.MESH | Phagocytosis/physiology* | - |
dc.subject.MESH | Silver/chemistry* | - |
dc.subject.MESH | Silver/pharmacology | - |
dc.title | Phagocytosis and endocytosis of silver nanoparticles induce interleukin-8 production in human macrophages | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Microbiology (미생물학) | - |
dc.contributor.googleauthor | Seungjae Kim | - |
dc.contributor.googleauthor | In-Hong Choi | - |
dc.identifier.doi | 10.3349/ymj.2012.53.3.654 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04167 | - |
dc.relation.journalcode | J02813 | - |
dc.identifier.eissn | 1976-2437 | - |
dc.identifier.pmid | 22477013 | - |
dc.subject.keyword | Silver nanoparticles | - |
dc.subject.keyword | macrophages | - |
dc.subject.keyword | endocytosis | - |
dc.subject.keyword | phagocytosis | - |
dc.subject.keyword | IL-8 | - |
dc.contributor.alternativeName | Choi, In Hong | - |
dc.contributor.affiliatedAuthor | Choi, In Hong | - |
dc.citation.volume | 53 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 654 | - |
dc.citation.endPage | 657 | - |
dc.identifier.bibliographicCitation | YONSEI MEDICAL JOURNAL, Vol.53(3) : 654-657, 2012 | - |
dc.identifier.rimsid | 29601 | - |
dc.type.rims | ART | - |
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