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Nutrition in patients on peritoneal dialysis

Authors
 Seung-Hyeok Han  ;  Dae-Suk Han 
Citation
 Nature Reviews. Nephrology, Vol.8(3) : 163-175, 2012 
Journal Title
 Nature Reviews. Nephrology 
ISSN
 1759-5061 
Issue Date
2012
Abstract
Protein-energy wasting (PEW) is prevalent among patients on dialysis and has emerged as an important risk factor for morbidity and mortality in these patients. Numerous factors, including inflammation, inadequate dialysis, insufficient nutrient intake, loss of protein during dialysis, chronic acidosis, hypercatabolic illness and comorbid conditions, are involved in the development of PEW. The causes and clinical features of PEW in patients on peritoneal dialysis and hemodialysis are comparable; assessment of the factors that lead to PEW in patients receiving peritoneal dialysis is important to ensure that PEW is managed correctly in these patients. For the past 20 years, much progress has been made in the prevention and treatment of PEW. However, the results of most nutritional intervention studies are inconclusive. In addition, the multifactorial and complicated pathogenesis of PEW makes it difficult to assess and treat. This Review summarizes the nutritional issues regarding the causes, assessment and treatment of PEW, with a focus on patients receiving peritoneal dialysis. In addition, an in-depth overview of the results of nutritional intervention studies is provided.
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/91507
DOI
10.1038/nrneph.2012.12
Appears in Collections:
1. Journal Papers (연구논문) > 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실)
Yonsei Authors
한대석(Han, Dae Suk) ; 한승혁(Han, Seung Hyeok)
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Full Text
http://www.nature.com/nrneph/journal/v8/n3/full/nrneph.2012.12.html
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