Comparison of the genetic structures surrounding qnrA1 in Korean Enterobacter cloacae and Chinese Escherichia coli strains isolated in the early 2000s: evidence for qnrA mobilization via Inc HI2 type plasmid

Sang Hoon Han; Young Ah Kim; Minggui Wang; Yangsoon Lee; Hae-Sun Chung; Jong Hwa Yum; Dongeun Yong; Kyungwon Lee; June Myung Kim

doi:22367953

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Comparison of the genetic structures surrounding qnrA1 in Korean Enterobacter cloacae and Chinese Escherichia coli strains isolated in the early 2000s: evidence for qnrA mobilization via Inc HI2 type plasmid

Authors: Sang Hoon Han ; Young Ah Kim ; Minggui Wang ; Yangsoon Lee ; Hae-Sun Chung ; Jong Hwa Yum ; Dongeun Yong ; Kyungwon Lee ; June Myung Kim

Citation: JOURNAL OF MICROBIOLOGY, Vol.50(1) : 166-169, 2012

Journal Title: JOURNAL OF MICROBIOLOGY

ISSN: 1225-8873

Issue Date: 2012

MeSH: Blotting, Southern ; China ; Enterobacter cloacae/genetics* ; Enterobacter cloacae/isolation & purification* ; Enterobacteriaceae Infections/microbiology* ; Escherichia coli/genetics* ; Escherichia coli/isolation & purification* ; Gene Order ; Gene Transfer, Horizontal* ; Genes, Bacterial* ; Humans ; Plasmids ; Republic of Korea ; Restriction Mapping ; Sequence Homology ; Synteny

Keywords: qnrA1 ; plasmid ; plasmid-mediated quinolone resistance ; gene mobilizat

Abstract: The flanking genetic structure of qnrA1 in Korean Enterobacter loacae was identical to that of the Chinese Escherichia coli strain, the first qnrA1-carrying strain reported in Asia. Analysis of restriction enzyme sites and Southern blot hybridization results showed that qnrA1 was transferred between E. cloacae and E. coli via Inc HI2 type plasmid.

Full Text: http://link.springer.com/article/10.1007%2Fs12275-012-1350-z

DOI: 22367953

Appears in Collections:: 1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers

Yonsei Authors: Kim, June Myung(김준명)
Yong, Dong Eun(용동은) https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) https://orcid.org/0000-0003-3788-2134
Lee, Yang Soon(이양순)
Chung, Hae Sun(정혜선)
Han, Sang Hoon(한상훈) https://orcid.org/0000-0002-4278-5198

URI: https://ir.ymlib.yonsei.ac.kr/handle/22282913/90966

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