Cited 9 times in

Prevalence and seroprevalence of low-risk human papillomavirus in Korean women

Authors
 Min-A Kim  ;  Jin-Kyoung Oh  ;  Bo Wook Kim  ;  Doobyung Chay  ;  Dong Choon Park  ;  Seok Mo Kim  ;  Eun-Suk Kang  ;  Jae-Hoon Kim  ;  Chi-Heum Cho  ;  Hai-Rim Shin  ;  Kyung Seo 
Citation
 JOURNAL OF KOREAN MEDICAL SCIENCE, Vol.27(8) : 922-928, 2012 
Journal Title
JOURNAL OF KOREAN MEDICAL SCIENCE
ISSN
 1011-8934 
Issue Date
2012
MeSH
Adolescent ; Adult ; Antibodies/blood ; Antibodies/immunology ; Child ; DNA, Viral/analysis ; Female ; Human papillomavirus 11/genetics ; Human papillomavirus 11/immunology ; Human papillomavirus 6/genetics ; Human papillomavirus 6/immunology ; Humans ; Middle Aged ; Odds Ratio ; Papillomavirus Infections/diagnosis ; Papillomavirus Infections/epidemiology* ; Prevalence ; Republic of Korea/epidemiology ; Risk Factors ; Seroepidemiologic Studies ; Sexual Behavior ; Young Adult
Keywords
Low-Risk Human Papillomavirus ; Prevalence ; Seroprevalence
Abstract
Little is known about the prevalence and seroprevalence of low-risk human papillomavirus (HPV) and the risk factors for HPV infection in Korean women. We determined the prevalence of low-risk HPV among 902 women aged 20-59 yr and the seroprevalence of low-risk HPV subtypes 6 and 11 among 1,094 women aged 9-59 yr in the general population. Genital low-risk HPV DNA was assessed by liquid hybridization and polymerase chain reaction. Antibody titers against HPV 6 and 11 were measured by a multiplexed competitive luminex technique. The prevalence of genital low-risk HPV was 4.9%. It reached its highest peak of 10.3% at 20-29 yr of age and a second peak of 3.2% at 50-59 yr of age. The seroprevalence of HPV 6 or 11 was 9.4%. It reached its highest peak of 12.7% at 25-29 yr of age and a second peak of 12.3% at 50-59 yr of age. In multivariable analysis, the number of lifetime sexual partners and past history of sexually transmitted diseases were associated with the seroprevalence but not prevalence of HPV. It is suggested that younger women should receive prophylactic HPV vaccination before they become sexually active and exposed to HPV in their 20s. This study provides baseline data for developing HPV vaccination programs and monitoring vaccine efficacy in Korea.
Files in This Item:
T201202503.pdf Download
DOI
10.3346/jkms.2012.27.8.922
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Obstetrics and Gynecology (산부인과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Bo Wook(김보욱)
Kim, Jae Hoon(김재훈) ORCID logo https://orcid.org/0000-0001-6599-7065
Seo, Kyung(서경)
Chay, Doo Byung(채두병) ORCID logo https://orcid.org/0000-0002-0648-4021
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90896
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links