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Comparison of three-year clinical outcomes with nonextended versus extended dual antiplatelet therapy between first- and second-generation drug-eluting stent implantation in patients with acute myocardial infarction: data from the infarct prognosis study registry
DC Field | Value | Language |
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dc.contributor.author | 홍명기 | - |
dc.contributor.author | 고영국 | - |
dc.contributor.author | 김병극 | - |
dc.contributor.author | 김중선 | - |
dc.contributor.author | 장양수 | - |
dc.contributor.author | 장지용 | - |
dc.contributor.author | 최동훈 | - |
dc.contributor.author | 하종원 | - |
dc.contributor.author | 이혜선 | - |
dc.date.accessioned | 2014-12-19T17:08:50Z | - |
dc.date.available | 2014-12-19T17:08:50Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0896-4327 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90863 | - |
dc.description.abstract | BACKGROUND: The difference of the clinical outcomes between nonextended (≤12 months) and extended (>12 months) dual antiplatelet therapy (DAPT) remains unclear in patients with acute myocardial infarction (AMI) implanted by different generations of drug-eluting stent (DES). METHODS: We identified 790 consecutive patients with AMI who were free from major adverse cardiac events for 12 months after first-generation (n = 537) or second-generation DES (n = 253) implantation; each DES generation group was further divided into nonextended and extended DAPT. RESULTS: During follow-up (median: 40 months), nonextended DAPT in the first-generation DES group showed a higher rate of cardiac death or MI than was observed in the extended DAPT group (14% vs 2%, P < 0.001). However, in the second-generation DES group, there was no difference in the occurrence of cardiac death and MI between the extended and nonextended groups (4% vs 3%, P = 0.809). Nonextended DAPT was the most significant predictor of cardiac death and MI for first-generation DES implantation [hazard ratio (HR) = 5.47, 95% confidence interval (CI) = 1.53-19.59, P = 0.009] but not for second-generation DES implantation [HR = 3.21, 95% CI = 0.21-50.65, P = 0.401]. CONCLUSION: This study suggested that the clinical outcomes between nonextended and extended DAPT might be different depending on the generation of implanted DESs in patients with AMI. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF INTERVENTIONAL CARDIOLOGY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Aged | - |
dc.subject.MESH | Angioplasty, Balloon, Coronary | - |
dc.subject.MESH | Coronary Artery Disease/drug therapy* | - |
dc.subject.MESH | Coronary Artery Disease/therapy | - |
dc.subject.MESH | Coronary Thrombosis/prevention & control | - |
dc.subject.MESH | Drug Administration Schedule | - |
dc.subject.MESH | Drug Therapy, Combination | - |
dc.subject.MESH | Drug-Eluting Stents*/adverse effects | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Follow-Up Studies | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Myocardial Infarction/drug therapy | - |
dc.subject.MESH | Myocardial Infarction/therapy* | - |
dc.subject.MESH | Platelet Aggregation Inhibitors/administration & dosage* | - |
dc.subject.MESH | Platelet Aggregation Inhibitors/adverse effects | - |
dc.subject.MESH | Prognosis | - |
dc.subject.MESH | Treatment Outcome | - |
dc.title | Comparison of three-year clinical outcomes with nonextended versus extended dual antiplatelet therapy between first- and second-generation drug-eluting stent implantation in patients with acute myocardial infarction: data from the infarct prognosis study registry | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Medical Engineering (의학공학) | - |
dc.contributor.googleauthor | KI-WOON KANG | - |
dc.contributor.googleauthor | BYEONG-KEUK KIM | - |
dc.contributor.googleauthor | JI-YONG JANG | - |
dc.contributor.googleauthor | HYE SUN LEE | - |
dc.contributor.googleauthor | JUNG-SUN KIM | - |
dc.contributor.googleauthor | YOUNG-GUK KO | - |
dc.contributor.googleauthor | JONGWON HA | - |
dc.contributor.googleauthor | DONGHOON CHOI | - |
dc.contributor.googleauthor | MYEONG-KI HONG | - |
dc.contributor.googleauthor | YANGSOO JANG | - |
dc.identifier.doi | 10.1111/j.1540-8183.2012.00719.x | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A04391 | - |
dc.contributor.localId | A00127 | - |
dc.contributor.localId | A00493 | - |
dc.contributor.localId | A00961 | - |
dc.contributor.localId | A03448 | - |
dc.contributor.localId | A04053 | - |
dc.contributor.localId | A04257 | - |
dc.contributor.localId | A03476 | - |
dc.contributor.localId | A03311 | - |
dc.relation.journalcode | J01465 | - |
dc.identifier.eissn | 1540-8183 | - |
dc.identifier.pmid | 22409626 | - |
dc.identifier.url | http://onlinelibrary.wiley.com/doi/10.1111/j.1540-8183.2012.00719.x/abstract | - |
dc.contributor.alternativeName | Hong, Myeong Ki | - |
dc.contributor.alternativeName | Ko, Young Guk | - |
dc.contributor.alternativeName | Kim, Byeong Keuk | - |
dc.contributor.alternativeName | Kim, Jung Sun | - |
dc.contributor.alternativeName | Lee, Hye Sun | - |
dc.contributor.alternativeName | Jang, Yang Soo | - |
dc.contributor.alternativeName | Jang, Ji Yong | - |
dc.contributor.alternativeName | Choi, Dong Hoon | - |
dc.contributor.alternativeName | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Hong, Myeong Ki | - |
dc.contributor.affiliatedAuthor | Ko, Young Guk | - |
dc.contributor.affiliatedAuthor | Kim, Byeong Keuk | - |
dc.contributor.affiliatedAuthor | Kim, Jung Sun | - |
dc.contributor.affiliatedAuthor | Jang, Yang Soo | - |
dc.contributor.affiliatedAuthor | Choi, Dong Hoon | - |
dc.contributor.affiliatedAuthor | Ha, Jong Won | - |
dc.contributor.affiliatedAuthor | Jang Ji Yong | - |
dc.contributor.affiliatedAuthor | Lee, Hye Sun | - |
dc.citation.volume | 25 | - |
dc.citation.number | 3 | - |
dc.citation.startPage | 245 | - |
dc.citation.endPage | 252 | - |
dc.identifier.bibliographicCitation | JOURNAL OF INTERVENTIONAL CARDIOLOGY, Vol.25(3) : 245-252, 2012 | - |
dc.identifier.rimsid | 34570 | - |
dc.type.rims | ART | - |
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