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Surgical results of Ahmed valve implantation with intraoperative bevacizumab injection in patients with neovascular glaucoma

DC FieldValueLanguage
dc.contributor.author김나래-
dc.contributor.author김지현-
dc.contributor.author김찬윤-
dc.contributor.author성공제-
dc.contributor.author이은석-
dc.contributor.author홍사민-
dc.date.accessioned2014-12-19T17:07:59Z-
dc.date.available2014-12-19T17:07:59Z-
dc.date.issued2012-
dc.identifier.issn1057-0829-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90838-
dc.description.abstractPURPOSE: To investigate the surgical results of Ahmed valve implantation with intraoperative bevacizumab injection in patients with neovascular glaucoma (NVG). METHODS: A retrospective comparative case series review was conducted on 52 eyes with NVG who underwent Ahmed glaucoma valve implantation with or without intraoperative bevacizumab intravitreal injection. In the intraoperative intravitreous bevacizumab injection group (IVB group, 20 eyes), 1.25 mg of bevacizumab was injected into the vitreous cavity during Ahmed valve implantation. In the control group (32 eyes), only Ahmed valve implantation was performed. Surgical failure was defined when (1) the postoperative intraocular pressure was over 21 mm Hg at consecutive clinic visits, (2) the visual acuity became light perception negative, (3) additional antiglaucomatic surgery was required, or (4) devastating operative or postoperative complications were noted. RESULTS: Although the success rate in the IVB group (70.0%) was higher than that in the control group (62.5%) 1 year after operation, the differences were not statistically significant (P=0.828 by log-rank test). Mean intraocular pressures in the IVB group were significantly lower than those of the control group at 12 and 15 months (P<0.05 by the Mann-Whitney U test). Postoperative complications were similar between the 2 groups. Preoperative history of trabeculectomy was a significant risk factor for surgical failure of Ahmed valve implantation in NVG (relative risk=4.618; P=0.018 by Cox regression model). CONCLUSIONS: Intraoperative IVB injection does not seem to be helpful for better surgical outcomes of Ahmed valve implantation in NVG. A history of trabeculectomy is a risk factor for failure after Ahmed valve implantation in patients with NVG.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJournal of Glaucoma-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleSurgical results of Ahmed valve implantation with intraoperative bevacizumab injection in patients with neovascular glaucoma-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Ophthalmology (안과학)-
dc.contributor.googleauthorMa, Kyoung Tak-
dc.contributor.googleauthorYang, Jong Yun-
dc.contributor.googleauthorKim, Ji Hyun-
dc.contributor.googleauthorKim, Na Rae-
dc.contributor.googleauthorHong, Samin-
dc.contributor.googleauthorLee, Eun Suk-
dc.contributor.googleauthorSeong, Gong Je-
dc.contributor.googleauthorKim, Chan Yun-
dc.identifier.doi10.1097/IJG.0b013e31820e2fd0-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00998-
dc.contributor.localIdA03036-
dc.contributor.localIdA00347-
dc.contributor.localIdA01035-
dc.contributor.localIdA01946-
dc.contributor.localIdA04395-
dc.relation.journalcodeJ01426-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00061198-201206000-00008&LSLINK=80&D=ovft-
dc.contributor.alternativeNameKim, Na Rae-
dc.contributor.alternativeNameKim, Ji Hyun-
dc.contributor.alternativeNameKim, Chan Yun-
dc.contributor.alternativeNameSeong, Gong Je-
dc.contributor.alternativeNameLee, Eun Suk-
dc.contributor.alternativeNameHong, Sa Min-
dc.contributor.affiliatedAuthorKim, Ji Hyun-
dc.contributor.affiliatedAuthorLee, Eun Suk-
dc.contributor.affiliatedAuthorKim, Na Rae-
dc.contributor.affiliatedAuthorKim, Chan Yun-
dc.contributor.affiliatedAuthorSeong, Gong Je-
dc.contributor.affiliatedAuthorHong, Sa Min-
dc.citation.volume21-
dc.citation.number5-
dc.citation.startPage331-
dc.citation.endPage336-
dc.identifier.bibliographicCitationJournal of Glaucoma, Vol.21(5) : 331-336, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Ophthalmology (안과학교실) > 1. Journal Papers

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