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Nosocomial clustering of NDM-1-producing Klebsiella pneumoniae sequence type 340 strains in four patients at a South Korean tertiary care hospital

Authors
 Mi-Na Kim  ;  Dongeun Yong  ;  Dongheui An  ;  Hae-Sun Chung  ;  Jun Hee Woo  ;  Kyungwon Lee  ;  Yunsop Chong 
Citation
 JOURNAL OF CLINICAL MICROBIOLOGY, Vol.50(4) : 1433-1436, 2012 
Journal Title
 JOURNAL OF CLINICAL MICROBIOLOGY 
ISSN
 0095-1137 
Issue Date
2012
MeSH
Aged ; Anti-Bacterial Agents/pharmacology ; Cluster Analysis ; Cross Infection/epidemiology ; Cross Infection/microbiology* ; Disk Diffusion Antimicrobial Tests ; Female ; Humans ; Klebsiella Infections/epidemiology ; Klebsiella Infections/microbiology* ; Klebsiella pneumoniae/classification ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/enzymology* ; Klebsiella pneumoniae/genetics ; Male ; Middle Aged ; Multilocus Sequence Typing ; Republic of Korea/epidemiology ; beta-Lactam Resistance/genetics ; beta-Lactamases/genetics* ; beta-Lactams/pharmacology
Keywords
Aged ; Anti-Bacterial Agents/pharmacology ; Cluster Analysis ; Cross Infection/epidemiology ; Cross Infection/microbiology* ; Disk Diffusion Antimicrobial Tests ; Female ; Humans ; Klebsiella Infections/epidemiology ; Klebsiella Infections/microbiology* ; Klebsiella pneumoniae/classification ; Klebsiella pneumoniae/drug effects ; Klebsiella pneumoniae/enzymology* ; Klebsiella pneumoniae/genetics ; Male ; Middle Aged ; Multilocus Sequence Typing ; Republic of Korea/epidemiology ; beta-Lactam Resistance/genetics ; beta-Lactamases/genetics* ; beta-Lactams/pharmacology
Abstract
In November 2010, NDM-1-producing Klebsiella pneumoniae (NDMKP) was identified for the first time in South Korea from four patients with no history of traveling abroad who stayed for 21 to 205 days in a tertiary care hospital. All were sequence type (ST) 340 and had nearly identical XbaI pulsed-field gel electrophoresis (PFGE) patterns. The bla(NDM-1)-carrying plasmids were in the IncN group, with sizes ranging from 50 to 200 kb. These findings suggest that NDMKP had already been introduced into South Korea before this clustering was found. 22259206
Files in This Item:
T201203842.pdf Download
DOI
22259206
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
Yonsei Authors
Yong, Dong Eun(용동은) ORCID logo https://orcid.org/0000-0002-1225-8477
Lee, Kyungwon(이경원) ORCID logo https://orcid.org/0000-0003-3788-2134
Chong, Yun Sop(정윤섭)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90696
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