Cited 9 times in
High-sensitivity C-reactive protein is independently associated with arterial stiffness in women with metabolic syndrome
DC Field | Value | Language |
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dc.contributor.author | 이정은 | - |
dc.contributor.author | 오의금 | - |
dc.contributor.author | 유재용 | - |
dc.date.accessioned | 2014-12-19T17:02:07Z | - |
dc.date.available | 2014-12-19T17:02:07Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0889-4655 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90654 | - |
dc.description.abstract | BACKGROUND: Metabolic syndrome (MetS) is associated with higher incidences of cardiovascular events and with increased mortality from coronary heart disease. There is increasing evidence that MetS presents as a proinflammatory and prothrombotic state. OBJECTIVES: The purposes of this study were to investigate the relationships among adiponectin (a marker for adipocytokines), high-sensitivity C-reactive protein (hs-CRP, a marker for inflammation), and brachial-ankle pulse-wave velocity (ba-PWV, a marker for arterial stiffness) in MetS and to identify predictors of ba-PWV, which indicates subclinical atherosclerosis. METHODS: The present study is a cross-sectional, secondary analysis of data collected as part of a longitudinal, randomized controlled trial that tested the effectiveness of a therapeutic lifestyle modification for Korean women with MetS (N = 52). We used the definition for MetS suggested by the National Cholesterol Education Program Adult Treatment Panel III. RESULTS: Adiponectin was negatively correlated with hs-CRP (r = -0.316, P = .027) and ba-PWV (r = -0.284, P = .048), and hs-CRP was positively correlated with ba-PWV (r = 0.341, P = .016). Women with high hs-CRP and low adiponectin levels also had greater ba-PWV levels (P = .041). Levels of hs-CRP were independently associated with ba-PWV after adjusting for age, body mass index, and number of MetS components, whereas no independent association was identified for adiponectin. CONCLUSION: Levels of hs-CRP may provide important prognostic information in terms of future cardiovascular risk in women with MetS. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | JOURNAL OF CARDIOVASCULAR NURSING | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Adiponectin/blood | - |
dc.subject.MESH | C-Reactive Protein/analysis* | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Metabolic Syndrome/blood* | - |
dc.subject.MESH | Metabolic Syndrome/physiopathology* | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Vascular Stiffness* | - |
dc.title | High-sensitivity C-reactive protein is independently associated with arterial stiffness in women with metabolic syndrome | - |
dc.type | Article | - |
dc.contributor.college | College of Nursing (간호대학) | - |
dc.contributor.department | Dept. of Nursing Environment SyStems (임상간호과학과) | - |
dc.contributor.googleauthor | Oh, Eui Geum | - |
dc.contributor.googleauthor | Kim, Soo Hyun | - |
dc.contributor.googleauthor | Bang, So Youn | - |
dc.contributor.googleauthor | Hyun, Sa Saeng | - |
dc.contributor.googleauthor | Im, Jee-Aee | - |
dc.contributor.googleauthor | Lee, Jung Eun | - |
dc.contributor.googleauthor | Yoo, Jae Yong | - |
dc.identifier.doi | 10.1097/JCN.0B013E31820E5A91 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A02393 | - |
dc.contributor.localId | A02498 | - |
dc.contributor.localId | A03120 | - |
dc.relation.journalcode | J01295 | - |
dc.identifier.eissn | 1550-5049 | - |
dc.identifier.pmid | 21372728 | - |
dc.identifier.url | http://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00005082-201201000-00009&LSLINK=80&D=ovft | - |
dc.subject.keyword | adiponectin | - |
dc.subject.keyword | arterial stiffness | - |
dc.subject.keyword | C-reactive protein | - |
dc.subject.keyword | metabolic syndrome | - |
dc.contributor.alternativeName | Lee, Jung Eun | - |
dc.contributor.alternativeName | Oh, Eui Geum | - |
dc.contributor.alternativeName | Yoo, Jae Yong | - |
dc.contributor.affiliatedAuthor | Oh, Eui Geum | - |
dc.contributor.affiliatedAuthor | Yoo, Jae Yong | - |
dc.contributor.affiliatedAuthor | Lee, Jung Eun | - |
dc.citation.volume | 27 | - |
dc.citation.number | 1 | - |
dc.citation.startPage | 61 | - |
dc.citation.endPage | 67 | - |
dc.identifier.bibliographicCitation | JOURNAL OF CARDIOVASCULAR NURSING, Vol.27(1) : 61-67, 2012 | - |
dc.identifier.rimsid | 33445 | - |
dc.type.rims | ART | - |
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