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Fungal peri-prosthetic joint infection after primary total knee replacement

Authors
 B-H. Hwang  ;  J-Y. Yoon  ;  C-H. Nam  ;  K-A. Jung  ;  S-C. Lee  ;  C-D. Han  ;  S-H. Moon 
Citation
 JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME , Vol.94(5) : 656-659, 2012 
Journal Title
 JOURNAL OF BONE AND JOINT SURGERY-BRITISH VOLUME 
ISSN
 0301-620X 
Issue Date
2012
MeSH
Aged ; Aged, 80 and over ; Antifungal Agents/administration & dosage ; Antifungal Agents/therapeutic use ; Arthroplasty, Replacement, Knee* ; Debridement/methods ; Device Removal ; Drug Administration Schedule ; Follow-Up Studies ; Humans ; Knee Prosthesis/adverse effects* ; Middle Aged ; Mycoses/surgery* ; Perioperative Care/methods ; Prosthesis-Related Infections/drug therapy ; Prosthesis-Related Infections/surgery* ; Recurrence ; Reoperation/methods ; Retrospective Studies ; Treatment Outcome
Keywords
Aged ; Aged, 80 and over ; Antifungal Agents/administration & dosage ; Antifungal Agents/therapeutic use ; Arthroplasty, Replacement, Knee* ; Debridement/methods ; Device Removal ; Drug Administration Schedule ; Follow-Up Studies ; Humans ; Knee Prosthesis/adverse effects* ; Middle Aged ; Mycoses/surgery* ; Perioperative Care/methods ; Prosthesis-Related Infections/drug therapy ; Prosthesis-Related Infections/surgery* ; Recurrence ; Reoperation/methods ; Retrospective Studies ; Treatment Outcome
Abstract
We retrospectively reviewed 30 two-stage revision procedures in 28 patients performed for fungal peri-prosthetic joint infection (PJI) after a primary total knee replacement. Patients were followed for at least two years or until the infection recurred. The mean follow-up for patients who remained free of infection was 4.3 years (2.3 to 6.1). Overall, 17 patients were assessed as American Society of Anesthesiologists grade 3 or 4. The surgical protocol included removal of the infected implant, vigorous debridement and insertion of an articulating cement spacer. This was followed by at least six weeks of antimicrobial treatment and delayed reimplantation in all patients. The mean interval between removal of the prosthesis and reimplantation was 9.5 weeks (6 to 24). After reimplantation, patients took antifungal agents orally for a maximum of six months. Two knees became reinfected at one and two months post-operatively, respectively: one of these subsequently required arthrodesis because of uncontrolled infection. Fungal PJIs can be treated successfully by removal of all infected material, appropriate antimicrobial treatment and delayed reimplantation.
Full Text
http://www.bjj.boneandjoint.org.uk/content/94-B/5/656.long
DOI
22529086
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Orthopedic Surgery (정형외과학교실) > 1. Journal Papers
Yonsei Authors
Moon, Seong Hwan(문성환)
Han, Chang Dong(한창동)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/90635
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