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Comparative evaluation of three calcium phosphate synthetic block bone graft materials for bone regeneration in rabbit calvaria

DC Field Value Language
dc.contributor.author최성호-
dc.contributor.author김창성-
dc.contributor.author이용근-
dc.contributor.author이중석-
dc.contributor.author정의원-
dc.date.accessioned2014-12-19T17:01:21Z-
dc.date.available2014-12-19T17:01:21Z-
dc.date.issued2012-
dc.identifier.issn1552-4973-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90631-
dc.description.abstractVarious synthetic materials were developed to be used for implant dentistry and periodontal treatments. Among the various synthetic bone substitutes, calcium phosphate ceramics have been extensively investigated because their mineral chemistry resembles that of human bone. We evaluated the regeneration of three calcium phosphate synthetic block bone grafts in rabbit calvarial noncritical size defects. Four 8-mm-diameter defects were created in each rabbit (N = 10). Three defects, hydroxyapatite (HA), beta-tricalcium phosphate (β-TCP), and biphasic calcium phosphate (BCP), were randomly filled with one of three fabricated synthetic block bone graft materials. The fourth defect was filled with blood clots. Specimens were harvested at 4 and 8 weeks postsurgery. Histological and histometrical findings indicated that all three calcium phosphate block bone graft materials were able to maintain space significantly better than the control group at both 4 and 8 weeks. In the BCP group, the amount of newly formed bone was increased more than for the other groups. Additionally, β-TCP showed a large resorption of graft materials after 4 weeks postsurgery, while there were only small resorption for HA and BCP.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAnimals-
dc.subject.MESHBone Regeneration*-
dc.subject.MESHBone Substitutes/chemistry-
dc.subject.MESHBone Substitutes/pharmacology*-
dc.subject.MESHCalcium Phosphates/chemistry-
dc.subject.MESHCalcium Phosphates/pharmacology*-
dc.subject.MESHDurapatite/chemistry-
dc.subject.MESHDurapatite/pharmacology*-
dc.subject.MESHHumans-
dc.subject.MESHHydroxyapatites/chemistry-
dc.subject.MESHHydroxyapatites/pharmacology*-
dc.subject.MESHMale-
dc.subject.MESHMaterials Testing/methods-
dc.subject.MESHRabbits-
dc.subject.MESHSkull-
dc.subject.MESHSkull Fractures/therapy*-
dc.subject.MESHTime Factors-
dc.titleComparative evaluation of three calcium phosphate synthetic block bone graft materials for bone regeneration in rabbit calvaria-
dc.typeArticle-
dc.contributor.collegeCollege of Dentistry (치과대학)-
dc.contributor.departmentDept. of Periodontology (치주과학)-
dc.contributor.googleauthorJi-Wan Hwang-
dc.contributor.googleauthorJae-Sub Park-
dc.contributor.googleauthorJung-Seok Lee-
dc.contributor.googleauthorUi-Won Jung-
dc.contributor.googleauthorChang-Sung Kim-
dc.contributor.googleauthorKyoo-Sung Cho-
dc.contributor.googleauthorYong-Keun Lee-
dc.contributor.googleauthorSeong-Ho Choi-
dc.identifier.doi22865716-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01041-
dc.contributor.localIdA02976-
dc.contributor.localIdA03692-
dc.contributor.localIdA03185-
dc.contributor.localIdA04081-
dc.relation.journalcodeJ01267-
dc.identifier.eissn1552-4981-
dc.identifier.pmid22865716-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1002/jbm.b.32768/abstract-
dc.subject.keywordbone regeneration-
dc.subject.keywordbiphasic calcium phosphate-
dc.subject.keywordhydroxyapatite-
dc.subject.keywordbeta-tricalcium phosphate-
dc.subject.keywordrabbit calvaria-
dc.contributor.alternativeNameChoi, Seong Ho-
dc.contributor.alternativeNameKim, Chang Sung-
dc.contributor.alternativeNameLee, Yong Keun-
dc.contributor.alternativeNameLee, Jung Seok-
dc.contributor.alternativeNameJung, Ui Won-
dc.contributor.affiliatedAuthorKim, Chang Sung-
dc.contributor.affiliatedAuthorLee, Yong Keun-
dc.contributor.affiliatedAuthorJung, Ui Won-
dc.contributor.affiliatedAuthorLee, Jung Seok-
dc.contributor.affiliatedAuthorChoi, Seong Ho-
dc.citation.volume100-
dc.citation.number8-
dc.citation.startPage2044-
dc.citation.endPage2052-
dc.identifier.bibliographicCitationJOURNAL OF BIOMEDICAL MATERIALS RESEARCH PART B-APPLIED BIOMATERIALS, Vol.100(8) : 2044-2052, 2012-
dc.identifier.rimsid32888-
dc.type.rimsART-
Appears in Collections:
2. College of Dentistry (치과대학) > Dept. of Dental Biomaterials and Bioengineering (치과생체재료공학교실) > 1. Journal Papers
2. College of Dentistry (치과대학) > Dept. of Periodontics (치주과학교실) > 1. Journal Papers

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