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염증성 장질환에서 5-aminosalicylate에 의해 발생한 재발성 급성 심낭염

Other Titles
 Recurrent Acute Pericarditis Induced by 5-aminosalicylates in a Patient with Inflammatory Bowel Disease 
 최아라  ;  김미나  ;  이지훈  ;  이용강  ;  박윤혜  ;  신혜선  ;  오탁근  ;  박희진  ;  박민석  ;  임승택  ;  박수정  ;  홍성필  ;  김태일  ;  김원호  ;  천재희 
 INTESTINAL RESEARCH, Vol.10(3) : 289-294, 2012 
Journal Title
Issue Date
Crohn Disease ; Colitis, Ulcerative ; Mesalamine ; Pericarditis
Inflammatory bowel disease (IBD) is an idiopathic chronic inflammation of the intestines. IBD treatment may require anti-inflammatory agents such as sulfasalazine or 5-aminosalicylate (5-ASA) and immunomodulators to control the symptoms. However, these agents have a variety of common adverse effects such as nausea, vomiting, skin rash, leukopenia, thrombocytopenia, and infections. Moreover, rare side effects such as nephrotic syndrome, pneumonitis, and pericarditis can occur. A 21-year-old male was admitted to the hospital due to acute chest pain, fever, and sweating. The patient had a history of Crohn's disease and had been taking mesalazine for 3 weeks. Chest x-ray, echocardiography, and clinical manifestations revealed that the patient had acute pericarditis. However, we did not recognize the relationship between these findings and 5-ASA at that time. Two years later, the patient took 5-ASA again, and similar symptoms occurred, which led us to confirm that he suffered from pericarditis induced by this drug. We report a case of acute recurrent pericarditis that developed after taking 5-ASA for IBD treatment with a review of the literature.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Kim, Mi Na(김미나)
Kim, Won Ho(김원호) ORCID logo https://orcid.org/0000-0002-5682-9972
Kim, Tae Il(김태일) ORCID logo https://orcid.org/0000-0003-4807-890X
Park, Soo Jung(박수정)
Park, Yoon Hea(박윤혜)
Park, Hee Jin(박희진)
Shin, Hye Sun(신혜선)
Oh, Tak Geun(오탁근)
Lee, Yong Kang(이용강)
Lee, Ji Hoon(이지훈)
Lim, Seung Taek(임승택)
Cheon, Jae Hee(천재희) ORCID logo https://orcid.org/0000-0002-2282-8904
Choi, A Ra(최아라)
Hong, Sung Pil(홍성필)
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