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Relationship between non-alcoholic fatty liver disease and pulmonary function.

DC FieldValueLanguage
dc.contributor.author문병수-
dc.contributor.author박병진-
dc.contributor.author심재용-
dc.contributor.author이용제-
dc.contributor.author이혜리-
dc.contributor.author정동혁-
dc.date.accessioned2014-12-19T16:54:40Z-
dc.date.available2014-12-19T16:54:40Z-
dc.date.issued2012-
dc.identifier.issn1444-0903-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90423-
dc.description.abstractBACKGROUND: It has been observed that non-alcoholic fatty liver disease (NAFLD) is associated with an increased risk of cardiovascular disease and insulin resistance. Pulmonary function is also known to be related with cardiovascular disease and metabolic syndrome. AIMS: The objective of this study was to investigate the association between NAFLD and pulmonary function. METHODS: We performed a cross-sectional study to examine the association of NAFLD based on abdominal sonographic findings and pulmonary function in 2119 Korean men between the ages of 30 and 75. Forced vital capacity (FVC) and forced expiratory volume in 1 s (FEV(1)) were compared according to the presence of NAFLD. Univariate and multivariate logistic regression analyses were conducted to evaluate the relationship of NAFLD with FVC and FEV(1) as pulmonary function tests. RESULTS: The subjects with NAFLD had lower FVC and FEV(1) than their non-steatotic counterparts, and FVC and FEV(1) gradually decreased according to the grade of hepatic steatosis. After adjusting for age, body mass index, smoking status, blood pressure, fasting plasma glucose, total cholesterol, hypertension, diabetes, triglyceride and high-density lipoprotein cholesterol, the FVC and FEV(1) were found to be inversely associated with the presence of NAFLD. CONCLUSION: NAFLD was independently associated with reduced pulmonary function, and the severity of NAFLD was inversely correlated with pulmonary function.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfINTERNAL MEDICINE JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAged-
dc.subject.MESHCardiovascular Diseases/epidemiology-
dc.subject.MESHCardiovascular Diseases/physiopathology-
dc.subject.MESHCross-Sectional Studies-
dc.subject.MESHFatty Liver/diagnosis-
dc.subject.MESHFatty Liver/epidemiology*-
dc.subject.MESHFatty Liver/physiopathology*-
dc.subject.MESHHumans-
dc.subject.MESHLung/physiology*-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHNon-alcoholic Fatty Liver Disease-
dc.subject.MESHRespiratory Function Tests/methods*-
dc.subject.MESHRespiratory Physiological Phenomena-
dc.subject.MESHRisk Factors-
dc.subject.MESHSurveys and Questionnaires-
dc.subject.MESHVital Capacity/physiology-
dc.titleRelationship between non-alcoholic fatty liver disease and pulmonary function.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorD.-H. Jung-
dc.contributor.googleauthorJ.-Y. Shim-
dc.contributor.googleauthorH.-R. Lee-
dc.contributor.googleauthorB.-S. Moon-
dc.contributor.googleauthorB.-J. Park-
dc.contributor.googleauthorY.-J. Lee-
dc.identifier.doi22181832-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01356-
dc.contributor.localIdA01477-
dc.contributor.localIdA02207-
dc.contributor.localIdA02982-
dc.contributor.localIdA03595-
dc.contributor.localIdA03310-
dc.relation.journalcodeJ01072-
dc.identifier.eissn1445-5994-
dc.identifier.pmid22181832-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/j.1445-5994.2011.02644.x/abstract-
dc.subject.keywordnon-alcoholic fatty liver disease-
dc.subject.keywordpulmonaryfunction-
dc.subject.keywordinflammation-
dc.contributor.alternativeNameMoon, Byung Soo-
dc.contributor.alternativeNamePark, Byoung Jin-
dc.contributor.alternativeNameShim, Jae Yong-
dc.contributor.alternativeNameLee, Yong Jae-
dc.contributor.alternativeNameLee, Hye Ree-
dc.contributor.alternativeNameJung, Dong Hyuk-
dc.contributor.affiliatedAuthorMoon, Byung Soo-
dc.contributor.affiliatedAuthorPark, Byoung Jin-
dc.contributor.affiliatedAuthorShim, Jae Yong-
dc.contributor.affiliatedAuthorLee, Yong Jae-
dc.contributor.affiliatedAuthorJung, Dong Hyuk-
dc.contributor.affiliatedAuthorLee, Hye Ree-
dc.citation.volume42-
dc.citation.number5-
dc.citation.startPage541-
dc.citation.endPage546-
dc.identifier.bibliographicCitationINTERNAL MEDICINE JOURNAL, Vol.42(5) : 541-546, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Family Medicine (가정의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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