248 591

Cited 0 times in

Balsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1

DC Field Value Language
dc.contributor.author박세은-
dc.contributor.author박은미-
dc.contributor.author석한나-
dc.contributor.author이병완-
dc.contributor.author이재현-
dc.contributor.author이지영-
dc.contributor.author이현철-
dc.contributor.author임승택-
dc.contributor.author차봉수-
dc.contributor.author강은석-
dc.date.accessioned2014-12-19T16:44:44Z-
dc.date.available2014-12-19T16:44:44Z-
dc.date.issued2012-
dc.identifier.issn2233-6079-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90113-
dc.description.abstractBACKGROUND: The aim of this study was to investigate the effects of balsamic vinegar on β-cell dysfunction. METHODS: In this study, 28-week-old Otsuka Long-Evans Tokushima Fatty (OLETF) rats were fed a normal chow diet or a high-fat diet (HFD) and were provided with tap water or dilute balsamic vinegar for 4 weeks. Oral glucose tolerance tests and histopathological analyses were performed thereafter. RESULTS: In rats fed both the both chow diet and the HFD, the rats given balsamic vinegar showed increased insulin staining in islets compared with tap water administered rats. Balsamic vinegar administration also increased β-cell ATP-binding cassette transporter subfamily A member 1 (ABCA1) expression in islets and decreased cholesterol levels. CONCLUSION: These findings provide the first evidence for an anti-diabetic effect of balsamic vinegar through improvement of β-cell function via increasing β-cell ABCA1 expression.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfDIABETES & METABOLISM JOURNAL-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleBalsamic Vinegar Improves High Fat-Induced Beta Cell Dysfunction via Beta Cell ABCA1-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorHannah Seok-
dc.contributor.googleauthorJi Young Lee-
dc.contributor.googleauthorEun Mi Park-
dc.contributor.googleauthorSe Eun Park-
dc.contributor.googleauthorJae Hyuk Lee-
dc.contributor.googleauthorSeungtaek Lim-
dc.contributor.googleauthorByung-Wan Lee-
dc.contributor.googleauthorEun Seok Kang-
dc.contributor.googleauthorHyun Chul Lee-
dc.contributor.googleauthorBong Soo Cha-
dc.identifier.doi22950058-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01521-
dc.contributor.localIdA01608-
dc.contributor.localIdA01930-
dc.contributor.localIdA02796-
dc.contributor.localIdA03086-
dc.contributor.localIdA03301-
dc.contributor.localIdA03380-
dc.contributor.localIdA03996-
dc.contributor.localIdA00068-
dc.relation.journalcodeJ00720-
dc.identifier.eissn2233-6087-
dc.identifier.pmid22950058-
dc.subject.keywordABCA1-
dc.subject.keywordBalsamic vinegar-
dc.subject.keywordDiet, high-fat-
dc.subject.keywordInsulin-
dc.subject.keywordIslets-
dc.contributor.alternativeNamePark, Se Eun-
dc.contributor.alternativeNamePark, Eun Mi-
dc.contributor.alternativeNameSeok, Hannah-
dc.contributor.alternativeNameLee, Byung Wan-
dc.contributor.alternativeNameLee, Jae Hyun-
dc.contributor.alternativeNameLee, Ji Young-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameLim, Seung Taek-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.alternativeNameKang, Eun Seok-
dc.contributor.affiliatedAuthorPark, Se Eun-
dc.contributor.affiliatedAuthorPark, Eun Mi-
dc.contributor.affiliatedAuthorSeok, Hannah-
dc.contributor.affiliatedAuthorLee, Byung Wan-
dc.contributor.affiliatedAuthorLee, Jae Hyun-
dc.contributor.affiliatedAuthorLee, Hyun Chul-
dc.contributor.affiliatedAuthorLim, Seung Taek-
dc.contributor.affiliatedAuthorCha, Bong Soo-
dc.contributor.affiliatedAuthorKang, Eun Seok-
dc.citation.volume36-
dc.citation.number4-
dc.citation.startPage275-
dc.citation.endPage279-
dc.identifier.bibliographicCitationDIABETES & METABOLISM JOURNAL, Vol.36(4) : 275-279, 2012-
dc.identifier.rimsid32369-
dc.type.rimsART-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.