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Cited 4 times in

Prevalence and determinants of coronary artery disease in first-degree relatives of premature coronary artery disease.

DC FieldValueLanguage
dc.contributor.author강민경-
dc.contributor.author박성하-
dc.contributor.author박애란-
dc.contributor.author장양수-
dc.contributor.author장혁재-
dc.contributor.author정남식-
dc.date.accessioned2014-12-19T16:43:34Z-
dc.date.available2014-12-19T16:43:34Z-
dc.date.issued2012-
dc.identifier.issn0954-6928-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/90075-
dc.description.abstractBACKGROUND: This study aimed to investigate the prevalence of subclinical coronary artery disease (CAD) in first-degree relatives (FDRs) with premature CAD and its associating factors other than conventional risk factors. METHODS: A total of 122 FDRs (58 men, 50±7 years) of patients with premature CAD were enrolled. The individuals who had undergone health checkups were included in the control group. Multidetector coronary computed tomography was performed to detect subclinical CAD. RESULTS: The prevalence of subclinical CAD (35 vs. 14%, P<0.001) and at least 50% subclinical CAD (16 vs. 2.5%, P<0.001) was higher in FDRs than that in the control group. In conditional regression analysis, the urinary albumin-creatinine ratio showed a significant interaction with CAD in FDRs than the control (odds ratio 1.063, 95% confidence interval 1.009-1.118, P=0.021). CONCLUSION: FDRs of premature CAD are more prevalent in subclinical CAD independent of conventional risk factors. Urinary albumin-creatinine ratio may have an interaction with the development of subclinical CAD in FDRs of premature CAD.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCoronary Artery Disease-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAdult-
dc.subject.MESHAlbumins/metabolism*-
dc.subject.MESHCase-Control Studies-
dc.subject.MESHCoronary Angiography-
dc.subject.MESHCoronary Artery Disease/epidemiology*-
dc.subject.MESHCoronary Artery Disease/urine-
dc.subject.MESHCreatinine/urine*-
dc.subject.MESHFamily*-
dc.subject.MESHFemale-
dc.subject.MESHHumans-
dc.subject.MESHMale-
dc.subject.MESHMiddle Aged-
dc.subject.MESHPrevalence-
dc.subject.MESHRepublic of Korea-
dc.subject.MESHRisk Factors-
dc.subject.MESHTomography, X-Ray Computed-
dc.titlePrevalence and determinants of coronary artery disease in first-degree relatives of premature coronary artery disease.-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Internal Medicine (내과학)-
dc.contributor.googleauthorKang, Min-Kyung-
dc.contributor.googleauthorChang, Hyuk-Jae-
dc.contributor.googleauthorKim, Young Jin-
dc.contributor.googleauthorPark, Ae Ran-
dc.contributor.googleauthorPark, Sungha-
dc.contributor.googleauthorJang, Yangsoo-
dc.contributor.googleauthorChung, Namsik-
dc.identifier.doi22421547-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA01512-
dc.contributor.localIdA01557-
dc.contributor.localIdA03448-
dc.contributor.localIdA03490-
dc.contributor.localIdA03585-
dc.contributor.localIdA00024-
dc.relation.journalcodeJ00649-
dc.identifier.pmid22421547-
dc.identifier.urlhttp://ovidsp.ovid.com/ovidweb.cgi?T=JS&CSC=Y&NEWS=N&PAGE=fulltext&AN=00019501-201205000-00005&LSLINK=80&D=ovft-
dc.subject.keywordpremature coronary artery disease-
dc.subject.keyword64-slice multi-detector computed tomography-
dc.subject.keywordurinary albumin excretion-
dc.contributor.alternativeNameKang, Min Kyung-
dc.contributor.alternativeNamePark, Sung Ha-
dc.contributor.alternativeNamePark, Ae Ran-
dc.contributor.alternativeNameJang, Yang Soo-
dc.contributor.alternativeNameChang, Hyuck Jae-
dc.contributor.alternativeNameChung, Nam Sik-
dc.contributor.affiliatedAuthorPark, Sung Ha-
dc.contributor.affiliatedAuthorPark, Ae Ran-
dc.contributor.affiliatedAuthorJang, Yang Soo-
dc.contributor.affiliatedAuthorChang, Hyuck Jae-
dc.contributor.affiliatedAuthorChung, Nam Sik-
dc.contributor.affiliatedAuthorKang, Min Kyung-
dc.citation.volume23-
dc.citation.number3-
dc.citation.startPage167-
dc.citation.endPage173-
dc.identifier.bibliographicCitationCoronary Artery Disease, Vol.23(3) : 167-173, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Medical Research Center (임상의학연구센터) > 1. Journal Papers

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