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Association between serum total bilirubin level and leukoaraiosis in Korean adults.
DC Field | Value | Language |
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dc.contributor.author | 강희택 | - |
dc.contributor.author | 박병진 | - |
dc.contributor.author | 심재용 | - |
dc.contributor.author | 이용제 | - |
dc.date.accessioned | 2014-12-19T16:41:24Z | - |
dc.date.available | 2014-12-19T16:41:24Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0009-9120 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/90005 | - |
dc.description.abstract | OBJECTIVES: Leukoaraiosis is associated with cerebrovascular microangiopathy. Increasing evidence suggests that bilirubin is a potent cytoprotectant in the development of cardiovascular diseases. This study aimed to determine whether total bilirubin is related to leukoaraiosis. METHODS: We examined the relationship of total bilirubin with leukoaraiosis in 1005 Korean adults. The odds ratios for leukoaraiosis were calculated using multivariate logistic regression across serum total bilirubin tertiles. RESULTS: In comparison with the subjects in the reference group (total bilirubin: 15-26 μmol/L), the odds ratio (95% CI) for leukoaraiosis in the 3rd tertile (total bilirubin ≤10 μmol/L) was 5.50 (1.24-24.40) in women after adjusting for confounding variables. However, this inverse association between serum total bilirubin and the prevalence of leukoaraiosis was not found in men after adjusting for the same co-variables. CONCLUSION: Total bilirubin level was inversely associated with leukoaraiosis regardless of classical cardiovascular risk factors in Korean women. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | CLINICAL BIOCHEMISTRY | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Bilirubin/blood* | - |
dc.subject.MESH | Cerebral Angiography | - |
dc.subject.MESH | Cross-Sectional Studies | - |
dc.subject.MESH | Female | - |
dc.subject.MESH | Hospitals, Urban | - |
dc.subject.MESH | Humans | - |
dc.subject.MESH | Leukoaraiosis/blood* | - |
dc.subject.MESH | Leukoaraiosis/epidemiology | - |
dc.subject.MESH | Leukoaraiosis/ethnology | - |
dc.subject.MESH | Magnetic Resonance Angiography | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Medical Records | - |
dc.subject.MESH | Middle Aged | - |
dc.subject.MESH | Prevalence | - |
dc.subject.MESH | Republic of Korea/epidemiology | - |
dc.subject.MESH | Retrospective Studies | - |
dc.subject.MESH | Risk Factors | - |
dc.subject.MESH | Sex Characteristics | - |
dc.title | Association between serum total bilirubin level and leukoaraiosis in Korean adults. | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Family Medicine (가정의학) | - |
dc.contributor.googleauthor | Byoung-Jin Parka | - |
dc.contributor.googleauthor | Jae-Yong Shima | - |
dc.contributor.googleauthor | Hye-Ree Leea | - |
dc.contributor.googleauthor | Hee-Taik Kanga | - |
dc.contributor.googleauthor | Jung-Hyun Leeb | - |
dc.contributor.googleauthor | Yong-Jae Leea | - |
dc.identifier.doi | 22245549 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A00106 | - |
dc.contributor.localId | A01477 | - |
dc.contributor.localId | A02207 | - |
dc.contributor.localId | A02982 | - |
dc.relation.journalcode | J00561 | - |
dc.identifier.eissn | 1873-2933 | - |
dc.identifier.pmid | 22245549 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0009912012000021 | - |
dc.subject.keyword | Bilirubin | - |
dc.subject.keyword | Leukoaraiosis | - |
dc.subject.keyword | Cerebral microangiopathy | - |
dc.contributor.alternativeName | Kang, Hee Taik | - |
dc.contributor.alternativeName | Park, Byoung Jin | - |
dc.contributor.alternativeName | Shim, Jae Yong | - |
dc.contributor.alternativeName | Lee, Yong Jae | - |
dc.contributor.affiliatedAuthor | Kang, Hee Taik | - |
dc.contributor.affiliatedAuthor | Park, Byoung Jin | - |
dc.contributor.affiliatedAuthor | Shim, Jae Yong | - |
dc.contributor.affiliatedAuthor | Lee, Yong Jae | - |
dc.citation.volume | 45 | - |
dc.citation.number | 4-5 | - |
dc.citation.startPage | 289 | - |
dc.citation.endPage | 292 | - |
dc.identifier.bibliographicCitation | CLINICAL BIOCHEMISTRY, Vol.45(4-5) : 289-292, 2012 | - |
dc.identifier.rimsid | 32301 | - |
dc.type.rims | ART | - |
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