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Comparison of clinical outcome of infrapopliteal angioplasty between Korean diabetic and non-diabetic patients with critical limb ischemia.

 Hyeon Min Ryu  ;  Jung-Sun Kim  ;  Young Guk Ko  ;  Myeong-Ki Hong  ;  Yangsoo Jang  ;  Dong-Hoon Choi 
 CIRCULATION JOURNAL, Vol.76(2) : 335-341, 2012 
Journal Title
Issue Date
Adult ; Aged ; Aged, 80 and over ; Angioplasty/methods ; Angioplasty/mortality* ; Diabetic Angiopathies/mortality* ; Diabetic Angiopathies/therapy* ; Female ; Follow-Up Studies ; Humans ; Ischemia/mortality* ; Ischemia/therapy* ; Kaplan-Meier Estimate ; Leg/blood supply ; Limb Salvage/methods ; Limb Salvage/mortality ; Male ; Middle Aged ; Multivariate Analysis ; Peripheral Arterial Disease/mortality ; Peripheral Arterial Disease/therapy ; Popliteal Artery/pathology* ; Republic of Korea/epidemiology
Angioplasty ; Critical limb ischemia ; Diabetes mellitus ; Infrapopliteal artery
BACKGROUND: Although infrapopliteal angioplasty may salvage the majority of limbs under threat of amputation, this procedure is still limited in diabetic patients. The purpose of the present study was to compared the outcomes of infrapopliteal angioplasty between Korean diabetic patients and non-diabetic patients with critical lower limb ischemia (CLI). METHODS AND RESULTS: Between March 2002 and May 2008, infrapopliteal angioplasty was performed on 108 limbs of 93 patients (71 male; mean age, 68 years, range, 27-91 years) with CLI (Rutherford-Becker category 4, 5 or 6). Freedom from reintervention, limb salvage, and overall survival were analyzed. Median follow-up was 30 months (range, 1-93 months). The number of diabetic patients was 70 (75%). There were no significant differences between the 2 groups in technical success rate (66% vs. 84%, P = 0.133) and primary clinical success rate (81% vs. 92%, P = 0.234). Kaplan-Meier analysis showed that diabetic patients had a higher frequency of poor primary patency (P = 0.012) during 2-year follow-up, but that there were no significant differences between the 2 groups in terms of limb salvage (P = 0.930), and survival (P = 0.459). CONCLUSIONS: Diabetic patients had an unfavorable 2-year primary patency compared with non-diabetic patients. There were no significant differences, however, between the 2 groups in terms of technical success rate, primary clinical success rate, 2-year limb salvage rate or overall survival.
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1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers
Yonsei Authors
Ko, Young Guk(고영국) ORCID logo https://orcid.org/0000-0001-7748-5788
Kim, Jung Sun(김중선) ORCID logo https://orcid.org/0000-0003-2263-3274
Jang, Yang Soo(장양수) ORCID logo https://orcid.org/0000-0002-2169-3112
Choi, Dong Hoon(최동훈) ORCID logo https://orcid.org/0000-0002-2009-9760
Hong, Myeong Ki(홍명기) ORCID logo https://orcid.org/0000-0002-2090-2031
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