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Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia.

Authors
 H. K. Kil  ;  W. O. Kim  ;  W. Y. Chung  ;  G. H. Kim  ;  H. Seo  ;  J.-Y. Hong 
Citation
 BRITISH JOURNAL OF ANAESTHESIA, Vol.108(1) : 119-125, 2012 
Journal Title
 BRITISH JOURNAL OF ANAESTHESIA 
ISSN
 0007-0912 
Issue Date
2012
MeSH
Adult ; Anesthesia, General* ; Anesthetics, Intravenous*/administration & dosage ; Anxiety/psychology* ; Consciousness Monitors ; Cross-Sectional Studies ; Female ; Hemodynamics/physiology ; Humans ; Male ; Methyl Ethers*/administration & dosage ; Middle Aged ; Oxygen/blood ; Pain/psychology* ; Pain Measurement ; Pain, Postoperative/epidemiology ; Pain, Postoperative/psychology ; Predictive Value of Tests ; Preoperative Period* ; Propofol*/administration & dosage ; Psychological Tests ; Thyroidectomy/adverse effects ; Young Adult
Keywords
anaesthesia, general ; anxiety ; pain threshold ; propofol, sevoflurane
Abstract
BACKGROUND: Psychological factors are thought to drive inter-patient variations in anaesthetic and analgesic requirements. This cross-sectional study investigated whether preoperative psychological factors can predict anaesthetic requirements and postoperative pain. METHODS: Before total thyroidectomy, 100 consecutive women completed the Spielberger's State-Trait Anxiety Inventory (STAI) and the pain sensitivity questionnaire (PSQ). Target-controlled propofol was administered for induction of anaesthesia, and sevoflurane-oxygen-air was given to maintain equal depths of anaesthesia, as determined by bispectral index (BIS) monitoring. RESULTS: Patients with higher anxiety scores (state and trait) required greater amounts of propofol to reach light (BIS=85) and moderate (BIS=75) levels of sedation, but only trait anxiety was significantly associated with propofol requirements in reaching a deep level of sedation (BIS=65). The MAC-hour of sevoflurane was significantly correlated only with PSQ scores. The postoperative pain intensity was significantly correlated with both STAI and PSQ. CONCLUSIONS: Preoperative anxiety and pain sensitivity are independent predictors of propofol and sevoflurane requirements in general anaesthesia. Anaesthetic and analgesic doses could be modified based on the patient's preoperative anxiety and pain sensitivity.
Files in This Item:
T201200029.pdf Download
DOI
22084330
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Surgery (외과학교실) > 1. Journal Papers
Yonsei Authors
Kil, Hae Keum(길혜금)
Kim, Won Oak(김원옥)
Chung, Woong Youn(정웅윤)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89821
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