Cited 12 times in
Evaluation of dopamine transporters and D2 receptors in hemiparkinsonian rat brains in vivo using consecutive PET scans of [18F]FPCIT and [18F]fallypride
DC Field | Value | Language |
---|---|---|
dc.contributor.author | 김동구 | - |
dc.contributor.author | 김철훈 | - |
dc.contributor.author | 유영훈 | - |
dc.contributor.author | 이민경 | - |
dc.contributor.author | 이종두 | - |
dc.contributor.author | 전태주 | - |
dc.date.accessioned | 2014-12-19T16:28:35Z | - |
dc.date.available | 2014-12-19T16:28:35Z | - |
dc.date.issued | 2012 | - |
dc.identifier.issn | 0969-8043 | - |
dc.identifier.uri | https://ir.ymlib.yonsei.ac.kr/handle/22282913/89599 | - |
dc.description.abstract | The aim of this study was to investigate dopaminergic function in unilaterally lesioned 6-OHDA rats by dual PET radioligands: [(18)F]FPCIT (a dopamine transporter imaging radioligand) and [(18)F]fallypride (a dopamine D2 receptors imaging radioligand). As a result, the brain uptake of [(18)F]FPCIT was significantly reduced and that of [(18)F]fallypride was increased in the ipsilateral striatum (lesion side) of the 6-OHDA rats. These findings implicated that dopamine transporter is down-regulated and dopamine D2 receptor is up-regulated in this hemiparkinsonian rat model. | - |
dc.description.statementOfResponsibility | open | - |
dc.relation.isPartOf | APPLIED RADIATION AND ISOTOPES | - |
dc.rights | CC BY-NC-ND 2.0 KR | - |
dc.rights.uri | https://creativecommons.org/licenses/by-nc-nd/2.0/kr/ | - |
dc.subject.MESH | Animals | - |
dc.subject.MESH | Benzamides* | - |
dc.subject.MESH | Corpus Striatum/diagnostic imaging | - |
dc.subject.MESH | Corpus Striatum/metabolism | - |
dc.subject.MESH | Dopamine Plasma Membrane Transport Proteins/metabolism* | - |
dc.subject.MESH | Down-Regulation | - |
dc.subject.MESH | Fluorine Radioisotopes* | - |
dc.subject.MESH | Male | - |
dc.subject.MESH | Oxidopamine | - |
dc.subject.MESH | Parkinsonian Disorders/chemically induced | - |
dc.subject.MESH | Parkinsonian Disorders/physiopathology* | - |
dc.subject.MESH | Positron-Emission Tomography/methods | - |
dc.subject.MESH | Rats | - |
dc.subject.MESH | Rats, Sprague-Dawley | - |
dc.subject.MESH | Receptors, Dopamine D2/metabolism* | - |
dc.subject.MESH | Tomography, Emission-Computed, Single-Photon | - |
dc.subject.MESH | Tropanes* | - |
dc.subject.MESH | Up-Regulation | - |
dc.title | Evaluation of dopamine transporters and D2 receptors in hemiparkinsonian rat brains in vivo using consecutive PET scans of [18F]FPCIT and [18F]fallypride | - |
dc.type | Article | - |
dc.contributor.college | College of Medicine (의과대학) | - |
dc.contributor.department | Dept. of Pharmacology (약리학) | - |
dc.contributor.googleauthor | Jae Yong Choi | - |
dc.contributor.googleauthor | Chul Hoon Kim | - |
dc.contributor.googleauthor | Tae Joo Jeon | - |
dc.contributor.googleauthor | Won Gil Cho | - |
dc.contributor.googleauthor | Jin Suk Lee | - |
dc.contributor.googleauthor | Soo Jin Lee | - |
dc.contributor.googleauthor | Tae Hyun Choi | - |
dc.contributor.googleauthor | Byoung Soo Kim | - |
dc.contributor.googleauthor | Chi Hoon Yi | - |
dc.contributor.googleauthor | Youngbeom Seo | - |
dc.contributor.googleauthor | Dae Ik Yi | - |
dc.contributor.googleauthor | Sang Jin Han | - |
dc.contributor.googleauthor | Minkyung Lee | - |
dc.contributor.googleauthor | Dong Goo Kim | - |
dc.contributor.googleauthor | Jong Doo Lee | - |
dc.contributor.googleauthor | Gwangil An | - |
dc.contributor.googleauthor | Young Hoon Ryu | - |
dc.identifier.doi | 10.1016/j.apradiso.2012.08.005 | - |
dc.admin.author | false | - |
dc.admin.mapping | false | - |
dc.contributor.localId | A03557 | - |
dc.contributor.localId | A00396 | - |
dc.contributor.localId | A01057 | - |
dc.contributor.localId | A02485 | - |
dc.contributor.localId | A02780 | - |
dc.contributor.localId | A03138 | - |
dc.relation.journalcode | J00206 | - |
dc.identifier.eissn | 1872-9800 | - |
dc.identifier.pmid | 23041777 | - |
dc.identifier.url | http://www.sciencedirect.com/science/article/pii/S0969804312004605 | - |
dc.subject.keyword | Animals | - |
dc.subject.keyword | Benzamides* | - |
dc.subject.keyword | Corpus Striatum/diagnostic imaging | - |
dc.subject.keyword | Corpus Striatum/metabolism | - |
dc.subject.keyword | Dopamine Plasma Membrane Transport Proteins/metabolism* | - |
dc.subject.keyword | Down-Regulation | - |
dc.subject.keyword | Fluorine Radioisotopes* | - |
dc.subject.keyword | Male | - |
dc.subject.keyword | Oxidopamine | - |
dc.subject.keyword | Parkinsonian Disorders/chemically induced | - |
dc.subject.keyword | Parkinsonian Disorders/physiopathology* | - |
dc.subject.keyword | Positron-Emission Tomography/methods | - |
dc.subject.keyword | Rats | - |
dc.subject.keyword | Rats, Sprague-Dawley | - |
dc.subject.keyword | Receptors, Dopamine D2/metabolism* | - |
dc.subject.keyword | Tomography, Emission-Computed, Single-Photon | - |
dc.subject.keyword | Tropanes* | - |
dc.subject.keyword | Up-Regulation | - |
dc.contributor.alternativeName | Kim, Dong Goo | - |
dc.contributor.alternativeName | Kim, Chul Hoon | - |
dc.contributor.alternativeName | Ryu, Young Hoon | - |
dc.contributor.alternativeName | Lee, Min Kyung | - |
dc.contributor.alternativeName | Lee, Jong Doo | - |
dc.contributor.alternativeName | Jeon, Tae Joo | - |
dc.contributor.affiliatedAuthor | Jeon, Tae Joo | - |
dc.contributor.affiliatedAuthor | Kim, Dong Goo | - |
dc.contributor.affiliatedAuthor | Kim, Chul Hoon | - |
dc.contributor.affiliatedAuthor | Ryu, Young Hoon | - |
dc.contributor.affiliatedAuthor | Lee, Min Kyung | - |
dc.contributor.affiliatedAuthor | Lee, Jong Doo | - |
dc.citation.volume | 70 | - |
dc.citation.number | 12 | - |
dc.citation.startPage | 2689 | - |
dc.citation.endPage | 2694 | - |
dc.identifier.bibliographicCitation | APPLIED RADIATION AND ISOTOPES, Vol.70(12) : 2689-2694, 2012 | - |
dc.identifier.rimsid | 32338 | - |
dc.type.rims | ART | - |
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