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Cited 9 times in

CD5-negative blastoid variant mantle cell lymphoma with complex CCND1/IGH and MYC aberrations

DC FieldValueLanguage
dc.contributor.author김수정-
dc.contributor.author김유리-
dc.contributor.author김주원-
dc.contributor.author박서진-
dc.contributor.author석윤미-
dc.contributor.author송재우-
dc.contributor.author이경아-
dc.contributor.author최종락-
dc.date.accessioned2014-12-19T16:25:50Z-
dc.date.available2014-12-19T16:25:50Z-
dc.date.issued2012-
dc.identifier.issn2234-3806-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89511-
dc.description.abstractThe coexistence of CCND1/IGH and MYC rearrangements in mantle cell lymphoma (MCL) is a rare finding associated with a very poor prognosis. In this study, a patient with blastoid variant (MCL) is reported. The disease was clinically aggressive and refractory to chemotherapy, and the patient only survived for 1 month following diagnosis. Conventional cytogenetic study, FISH, and multicolor FISH (mFISH) demonstrated the involvement of the BCL1/CCND1 locus in a complex translocation, t(3;11)(q25;p15)t(11;14)(q13;q32). In addition, subclonal abnormalities in the 8q24 region, manifested as a t(8;14)(q24;q32)/MYC rearrangement, were identified. To the best of our knowledge, this is the first MCL case in Korea bearing these complex genomic aberrations.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfAnnals of Laboratory Medicine-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.subject.MESHAged, 80 and over-
dc.subject.MESHBone Marrow/immunology-
dc.subject.MESHBone Marrow/metabolism-
dc.subject.MESHCD5 Antigens/metabolism*-
dc.subject.MESHChromosomes, Human, Pair 11-
dc.subject.MESHChromosomes, Human, Pair 14-
dc.subject.MESHChromosomes, Human, Pair 3-
dc.subject.MESHGene Rearrangement-
dc.subject.MESHHumans-
dc.subject.MESHImmunophenotyping-
dc.subject.MESHIn Situ Hybridization, Fluorescence-
dc.subject.MESHLymphoma, Mantle-Cell/diagnosis*-
dc.subject.MESHLymphoma, Mantle-Cell/genetics-
dc.subject.MESHLymphoma, Mantle-Cell/immunology-
dc.subject.MESHMale-
dc.subject.MESHOncogene Proteins, Fusion/genetics*-
dc.subject.MESHProto-Oncogene Proteins c-myc/genetics*-
dc.subject.MESHTranslocation, Genetic-
dc.titleCD5-negative blastoid variant mantle cell lymphoma with complex CCND1/IGH and MYC aberrations-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentDept. of Laboratory Medicine (진단검사의학)-
dc.contributor.googleauthorYoonmi Seok-
dc.contributor.googleauthorJuwon Kim-
dc.contributor.googleauthorJong Rak Choi-
dc.contributor.googleauthorYu Ri Kim-
dc.contributor.googleauthorSeo-Jin Park-
dc.contributor.googleauthorSue Jung Kim-
dc.contributor.googleauthorJaewoo song-
dc.contributor.googleauthorKyung-A Lee-
dc.identifier.doi22259787-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00634-
dc.contributor.localIdA00943-
dc.contributor.localIdA01494-
dc.contributor.localIdA01927-
dc.contributor.localIdA02054-
dc.contributor.localIdA02647-
dc.contributor.localIdA04182-
dc.contributor.localIdA00779-
dc.relation.journalcodeJ00164-
dc.identifier.pmid22259787-
dc.subject.keywordCCND1-
dc.subject.keywordMYC-
dc.subject.keywordMantle cell lymphoma-
dc.contributor.alternativeNameKim, Sue Jeong-
dc.contributor.alternativeNameKim, Yu Ri-
dc.contributor.alternativeNameKim, Ju Won-
dc.contributor.alternativeNamePark, Seo Jin-
dc.contributor.alternativeNameSeok, Yoon Mi-
dc.contributor.alternativeNameSong, Jae Woo-
dc.contributor.alternativeNameLee, Kyung A-
dc.contributor.alternativeNameChoi, Jong Rak-
dc.contributor.affiliatedAuthorKim, Sue Jeong-
dc.contributor.affiliatedAuthorKim, Ju Won-
dc.contributor.affiliatedAuthorPark, Seo Jin-
dc.contributor.affiliatedAuthorSeok, Yoon Mi-
dc.contributor.affiliatedAuthorSong, Jae Woo-
dc.contributor.affiliatedAuthorLee, Kyung A-
dc.contributor.affiliatedAuthorChoi, Jong Rak-
dc.contributor.affiliatedAuthorKim, Yu Ri-
dc.citation.volume32-
dc.citation.number1-
dc.citation.startPage95-
dc.citation.endPage98-
dc.identifier.bibliographicCitationAnnals of Laboratory Medicine, Vol.32(1) : 95-98, 2012-
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Laboratory Medicine (진단검사의학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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