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Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia

Authors
 H. Kim  ;  S.-H. Choi  ;  Y.-S. Choi  ;  J.-H. Lee  ;  N.-O. Kim  ;  J.-R. Lee 
Citation
 Anaesthesia, Vol.67(7) : 765-770, 2012 
Journal Title
 Anaesthesia 
ISSN
 0003-2409 
Issue Date
2012
Abstract
This prospective randomised study compared the antitussive effect of remifentanil during recovery from either propofol or sevoflurane anaesthesia. Seventy-four female patients undergoing thyroidectomy were anaesthetised with either propofol and remifentanil or sevoflurane and remifentanil. During recovery, remifentanil was maintained at an effect-site concentration of 2 ng.ml(-1) until extubation and the occurrence of coughing, haemodynamic parameters and recovery profiles were compared between the two groups. During recovery, neither the incidence nor the severity of cough (incidence 20% with propofol; 24% with sevoflurane, p = 0.77), nor the haemodynamic parameters were different between the two groups. Time to awakening and time to extubation were significantly shorter in the propofol group (4.7 min, 6.1 min min, respectively) compared with the sevoflurane group (7.9 min and 8.9 min respectively) (p < 0.001 and p = 0.002, respectively). An effect-site concentration of 2 ng.ml(-1) of remifentanil was associated with smooth emergence from both propofol and sevoflurane anaesthesia.
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2044.2012.07136.x
DOI
10.1111/j.1365-2044.2012.07136.x
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
김현주B(Kim, Hyun Zu)
이재훈(Lee, Jae Hoon) ORCID logo https://orcid.org/0000-0001-6679-2782
이정림(Lee, Jeong Rim) ORCID logo https://orcid.org/0000-0002-7425-0462
최승호(Choi, Seung Ho) ORCID logo https://orcid.org/0000-0001-8442-4406
최용선(Choi, Yong Seon) ORCID logo https://orcid.org/0000-0002-5348-864X
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URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89465
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