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Comparison of the antitussive effect of remifentanil during recovery from propofol and sevoflurane anaesthesia

Authors
 H. Kim  ;  S.-H. Choi  ;  Y.-S. Choi  ;  J.-H. Lee  ;  N.-O. Kim  ;  J.-R. Lee 
Citation
 ANAESTHESIA, Vol.67(7) : 765-770, 2012 
Journal Title
 ANAESTHESIA 
ISSN
 0003-2409 
Issue Date
2012
MeSH
Adult ; Aged ; Anesthesia Recovery Period ; Anesthetics, Inhalation/adverse effects ; Anesthetics, Intravenous/adverse effects ; Antitussive Agents/therapeutic use* ; Blood Pressure/drug effects ; Cough/etiology ; Cough/prevention & control* ; Device Removal/adverse effects ; Female ; Heart Rate/drug effects ; Humans ; Intubation, Intratracheal ; Methyl Ethers/adverse effects* ; Middle Aged ; Piperidines/therapeutic use* ; Postoperative Complications/prevention & control ; Propofol/adverse effects* ; Prospective Studies ; Single-Blind Method ; Thyroidectomy ; Young Adult
Keywords
Adult ; Aged ; Anesthesia Recovery Period ; Anesthetics, Inhalation/adverse effects ; Anesthetics, Intravenous/adverse effects ; Antitussive Agents/therapeutic use* ; Blood Pressure/drug effects ; Cough/etiology ; Cough/prevention & control* ; Device Removal/adverse effects ; Female ; Heart Rate/drug effects ; Humans ; Intubation, Intratracheal ; Methyl Ethers/adverse effects* ; Middle Aged ; Piperidines/therapeutic use* ; Postoperative Complications/prevention & control ; Propofol/adverse effects* ; Prospective Studies ; Single-Blind Method ; Thyroidectomy ; Young Adult
Abstract
This prospective randomised study compared the antitussive effect of remifentanil during recovery from either propofol or sevoflurane anaesthesia. Seventy-four female patients undergoing thyroidectomy were anaesthetised with either propofol and remifentanil or sevoflurane and remifentanil. During recovery, remifentanil was maintained at an effect-site concentration of 2 ng.ml(-1) until extubation and the occurrence of coughing, haemodynamic parameters and recovery profiles were compared between the two groups. During recovery, neither the incidence nor the severity of cough (incidence 20% with propofol; 24% with sevoflurane, p = 0.77), nor the haemodynamic parameters were different between the two groups. Time to awakening and time to extubation were significantly shorter in the propofol group (4.7 min, 6.1 min min, respectively) compared with the sevoflurane group (7.9 min and 8.9 min respectively) (p < 0.001 and p = 0.002, respectively). An effect-site concentration of 2 ng.ml(-1) of remifentanil was associated with smooth emergence from both propofol and sevoflurane anaesthesia.
Full Text
https://onlinelibrary.wiley.com/doi/abs/10.1111/j.1365-2044.2012.07136.x
DOI
22519849
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Anesthesiology and Pain Medicine (마취통증의학교실) > 1. Journal Papers
Yonsei Authors
Kim, Hyun Zu(김현주B)
Lee, Jae Hoon(이재훈) ORCID logo https://orcid.org/0000-0001-6679-2782
Lee, Jeong Rim(이정림) ORCID logo https://orcid.org/0000-0002-7425-0462
Choi, Seung Ho(최승호) ORCID logo https://orcid.org/0000-0001-8442-4406
Choi, Yong Seon(최용선) ORCID logo https://orcid.org/0000-0002-5348-864X
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89465
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