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Parainfluenza virus 감영 후 발생한 횡문근융해증과 isovaleric acidemia로 인한 고암모니아혈증을 가진 소아에서의 지속적 신대체요법

Other Titles
 Continuous Renal Replacement Therapy in a 4-year-old Child with Rhabdomyolysis Following Parainfluenza Virus Infection and Hyperammonemia due to Isovaleric Acidemia 
Authors
 Se Jin Park  ;  Soo Yeon Cho  ;  Ki Soo Pai  ;  Jae Il Shin 
Citation
 Journal of the Korean Society of Pediatric Nephrology (대한소아신장학회지), Vol.17(2) : 132-136, 2013 
Journal Title
Journal of the Korean Society of Pediatric Nephrology(대한소아신장학회지)
ISSN
 1226-5292 
Issue Date
2013
Keywords
Rhabdomyolysis ; Hyperammonemia ; Parainfluenza virus ; Isovaleric acidemia ; Continuous renal replacement therapy
Abstract
Parainfluenza virus infection is one of the causes of fatal rhabdomyolysis. Rhabdomyolysis can be aggravated by mitochondrial fatty acid β-oxidation disorders during prolonged periods of fasting. Moreover, in patients with late-onset isovaleric acidemia, hyperammonemia may occur following catabolic stress. In the present report, we describe a case of a 4-year-old boy with parainfluenza virus infection and late-onset isovaleric acidemia that rapidly progressed to coma, seizures, and cardiorespiratory collapse. His serum ammonia and creatinine kinase (CK) levels were 385 µMol/L and 23,707 IU/L, respectively. Continuous renal replacement therapy (CRRT) was initiated using continuous venovenous hemodiafiltration, after which the ammonia and CK levels returned to normal. Thus, we recommend the immediate initiation of CRRT in the management of patients with life-threatening rhabdomyolysis and hyperammonemia.
Files in This Item:
T201305643.pdf Download
DOI
10.3339/jkspn.2013.17.2.132
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Pediatrics (소아과학교실) > 1. Journal Papers
Yonsei Authors
Shin, Jae Il(신재일) ORCID logo https://orcid.org/0000-0003-2326-1820
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/89144
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