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Transcription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor γ

DC FieldValueLanguage
dc.contributor.author강은석-
dc.contributor.author김수현-
dc.contributor.author김재우-
dc.contributor.author이병완-
dc.contributor.author이용호-
dc.contributor.author이유정-
dc.contributor.author이현철-
dc.contributor.author차봉수-
dc.date.accessioned2014-12-18T09:56:15Z-
dc.date.available2014-12-18T09:56:15Z-
dc.date.issued2013-
dc.identifier.issn1420-682X-
dc.identifier.urihttps://ir.ymlib.yonsei.ac.kr/handle/22282913/89110-
dc.description.abstractEpidermolysis bullosa acquisita (EBA) is a chronic autoimmune subepidermal bullous disease with clinical features similar to the genetic form of dystrophic epidermolysis bullosa. EBA is characterized by the presence of autoantibodies against type VII collagen which is a major component of the anchoring fibrils at the dermal-epidermal junction. EBA can be divided into two main clinical types; mechanobullous and inflammatory EBA. Mechanobullous EBA, referred to as classic EBA, presents with skin fragility, blisters and dystrophic changes on trauma-prone areas. Inflammatory EBA resembles other autoimmune subepidermal bullous diseases. Compelling evidence from mouse models supports a pathogenic role of autoantibodies against type VII collagen in EBA. Treatment of EBA is often unsatisfactory. The most widely used systemic treatment is corticosteroids. Colchicine and dapsone have been reported to be good treatment modalities when combined with corticosteroids. Some intractable cases of EBA have successfully been treated with intravenous immunoglobulin or rituximab.-
dc.description.statementOfResponsibilityopen-
dc.relation.isPartOfCELLULAR AND MOLECULAR LIFE SCIENCES-
dc.rightsCC BY-NC-ND 2.0 KR-
dc.rights.urihttps://creativecommons.org/licenses/by-nc-nd/2.0/kr/-
dc.titleTranscription factor Snail is a novel regulator of adipocyte differentiation via inhibiting the expression of peroxisome proliferator-activated receptor γ-
dc.typeArticle-
dc.contributor.collegeCollege of Medicine (의과대학)-
dc.contributor.departmentYonsei Biomedical Research Center (연세의생명연구원)-
dc.contributor.googleauthorYong-ho Lee-
dc.contributor.googleauthorSoo Hyun Kim-
dc.contributor.googleauthorYoo Jeong Lee-
dc.contributor.googleauthorEun Seok Kang-
dc.contributor.googleauthorByung-Wan Lee-
dc.contributor.googleauthorBong Soo Cha-
dc.contributor.googleauthorJae Woo Kim-
dc.contributor.googleauthorDae Hyun Song-
dc.contributor.googleauthorHyun Chul Lee-
dc.identifier.doi10.1007/s00018-013-1363-8-
dc.admin.authorfalse-
dc.admin.mappingfalse-
dc.contributor.localIdA00068-
dc.contributor.localIdA00865-
dc.contributor.localIdA02796-
dc.contributor.localIdA02989-
dc.contributor.localIdA03014-
dc.contributor.localIdA03301-
dc.contributor.localIdA03996-
dc.contributor.localIdA00641-
dc.relation.journalcodeJ00496-
dc.identifier.eissn1420-9071-
dc.identifier.urlhttp://onlinelibrary.wiley.com/doi/10.1111/jdv.12096/abstract-
dc.contributor.alternativeNameKang, Eun Seok-
dc.contributor.alternativeNameKim, Soo Hyun-
dc.contributor.alternativeNameKim, Jae Woo-
dc.contributor.alternativeNameLee, Byung Wan-
dc.contributor.alternativeNameLee, Yong Ho-
dc.contributor.alternativeNameLee, Yoo Jeong-
dc.contributor.alternativeNameLee, Hyun Chul-
dc.contributor.alternativeNameCha, Bong Soo-
dc.contributor.affiliatedAuthorKang, Eun Seok-
dc.contributor.affiliatedAuthorKim, Jae Woo-
dc.contributor.affiliatedAuthorLee, Byung Wan-
dc.contributor.affiliatedAuthorLee, Yong Ho-
dc.contributor.affiliatedAuthorLee, Yoo Jeong-
dc.contributor.affiliatedAuthorLee, Hyun Chul-
dc.contributor.affiliatedAuthorCha, Bong Soo-
dc.contributor.affiliatedAuthorKim, Soo Hyun-
dc.rights.accessRightsnot free-
dc.citation.volume70-
dc.citation.number20-
dc.citation.startPage3959-
dc.citation.endPage3971-
dc.identifier.bibliographicCitationCELLULAR AND MOLECULAR LIFE SCIENCES, Vol.70(20) : 3959-3971, 2013-
Appears in Collections:
1. College of Medicine (의과대학) > Yonsei Biomedical Research Center (연세의생명연구원) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Biochemistry and Molecular Biology (생화학-분자생물학교실) > 1. Journal Papers
1. College of Medicine (의과대학) > Dept. of Internal Medicine (내과학교실) > 1. Journal Papers

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