251 382

Cited 1 times in

Is tinnitus accompanied by hemifacial spasm in normal-hearing patients also a type of hyperactive neurovascular compression syndrome? : A magnetoencephalography study

Authors
 Won Seok Chang  ;  Bong Soo Kim  ;  Ji Eun Lee  ;  Hyun Ho Jung  ;  Kiwoong Kim  ;  Hyuk Chan Kwon  ;  Yong Ho Lee  ;  Jin Woo Chang 
Citation
 BMC NEUROLOGY, Vol.13 : 42, 2013 
Journal Title
BMC NEUROLOGY
Issue Date
2013
MeSH
Acoustic Stimulation ; Adult ; Aged ; Electroencephalography ; Evoked Potentials, Auditory/physiology ; Female ; Functional Laterality/physiology ; Hemifacial Spasm/complications* ; Humans ; Magnetic Resonance Imaging ; Magnetoencephalography* ; Male ; Middle Aged ; Nerve Compression Syndromes/complications* ; Reaction Time/physiology ; Tinnitus/diagnosis* ; Tinnitus/etiology*
Keywords
Hemifacial spasm ; Magnetoencephalography ; Pathophysiology ; Tinnitus
Abstract
BACKGROUND:
Traditionally, tinnitus accompanied by hemifacial spasm has been considered a type of hyperactive neurovascular compression syndrome that is similar to hemifacial spasm alone because of the anatomically close relationship between the facial nerve and cochlear nerve as well as the hyperactive clinical nature.
METHODS:
Participants were 29 subjects who presented with hemifacial spasm and neuroradiological evidence of vascular compression of the cranial (facial/cochlear) nerve. We used magnetoencephalography (MEG) to estimate the activity of the cochlear nerve in patients with and without tinnitus on the ipsilateral side. We compared the difference in the latency and the ratio of the equivalent current dipole (ECD) strength between the ipsilateral and contralateral sides of the spasm and tinnitus.
RESULTS:
Cochlear nerve activity in patients with tinnitus was increased with a shorter latency (p = 0.016) and stronger ECD strength (p = 0.028) compared with patients without tinnitus.
CONCLUSION:
The MEG results from normal-hearing patients who had tinnitus accompanied by hemifacial spasm suggest that the hyperactivity of the auditory central nervous system may be a crucial pathophysiological factor in the generation of tinnitus in these patients. The neurovascular compression that causes sensory input from the pathologic facial nerve activity may contribute to this hyperactivity of the central auditory nervous system.
Files in This Item:
T201305245.pdf Download
DOI
10.1186/1471-2377-13-42
Appears in Collections:
1. College of Medicine (의과대학) > Dept. of Neurosurgery (신경외과학교실) > 1. Journal Papers
Yonsei Authors
Chang, Won Seok(장원석) ORCID logo https://orcid.org/0000-0003-3145-4016
Chang, Jin Woo(장진우) ORCID logo https://orcid.org/0000-0002-2717-0101
Jung, Hyun Ho(정현호)
URI
https://ir.ymlib.yonsei.ac.kr/handle/22282913/88864
사서에게 알리기
  feedback

qrcode

Items in DSpace are protected by copyright, with all rights reserved, unless otherwise indicated.

Browse

Links