First Outbreak of KPC-2-Producing Klebsiella pneumoniae Sequence Type 258 in a Hospital in South Korea

407 564

Cited 26 times in

Authors: Sung Kwan Hong ; Dongeun Yong ; Kyeongmi Kim ; Sang Sook Hong ; Seong Geun Hong ; Tulgaa Khosbayar ; Wonkeun Song ; Kyoung Ho Roh ; Seok Hoon Jeong ; Kyungwon Lee ; Yunsop Chong

MeSH: Aged ; Anti-Bacterial Agents/pharmacology ; Cluster Analysis ; Disease Outbreaks* ; Genotype ; Hospitals ; Humans ; Klebsiella Infections/epidemiology* ; Klebsiella Infections/microbiology* ; Klebsiella pneumoniae/classification ; Klebsiella pneumoniae/enzymology* ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification* ; Microbial Sensitivity Tests ; Middle Aged ; Multilocus Sequence Typing ; Republic of Korea/epidemiology ; beta-Lactamases/genetics ; beta-Lactamases/secretion*

Keywords: Aged ; Anti-Bacterial Agents/pharmacology ; Cluster Analysis ; Disease Outbreaks* ; Genotype ; Hospitals ; Humans ; Klebsiella Infections/epidemiology* ; Klebsiella Infections/microbiology* ; Klebsiella pneumoniae/classification ; Klebsiella pneumoniae/enzymology* ; Klebsiella pneumoniae/genetics ; Klebsiella pneumoniae/isolation & purification* ; Microbial Sensitivity Tests ; Middle Aged ; Multilocus Sequence Typing ; Republic of Korea/epidemiology ; beta-Lactamases/genetics ; beta-Lactamases/secretion*

Abstract: In this study, we report the first outbreak of KPC-2-producing Klebsiella pneumoniae isolates from three patients admitted to a neurosurgery department in a South Korean teaching hospital. Multilocus sequence typing showed that the isolates were identical to the previous KPC producers in South Korea and other countries, suggesting clonal spread.